血吸虫病疫情控制地区查病方案研究  被引量:3

Study on scheme of field screening in transmission-controlled areas of schistosomiasis

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作  者:孙乐平[1] 洪青标[1] 黄轶昕[1] 梁幼生[1] 徐明[1] 马玉才[2] 高扬 李伟[1] 杨坤[1] 朱荫昌[1] 

机构地区:[1]江苏省血吸虫病防治研究所,无锡214064 [2]江苏省扬州市邗江区疾病预防控制中心 [3]江苏省扬州市血吸虫病防治所

出  处:《中国血吸虫病防治杂志》2006年第4期256-260,共5页Chinese Journal of Schistosomiasis Control

基  金:江苏省卫生厅重大项目(H2006)

摘  要:目的 探讨适合血吸虫病疫情控制地区的查病方案。方法 选择江滩型血吸虫病流行区的扬州市邗江区沿江村6~65岁人群作为查病对象,按照单盲试验的原则,同时用DDIA4-Kato-Katz法、DDIA+集卵孵化法、ELISA+Kato-Katz法和ELISA+集卵孵化法4种查病方案进行查病,分析病人漏检原因,比较各种查病方案的漏检率和查病费用。结果 对1251人进行了查病,受检率为92.19%,共查出血清学阳性298例,粪检阳性29例。其中DDIA+KatoKatz法、DDIA+集卵孵化法、ELISA+Kato-Katz法和ELISA+集卵孵化法4种查病方案分别查出粪检阳性病人19、26、19例和24例,分别漏检10、3、10例和5例,漏检率分别为34.48%、10.34%、34.48%和17.24%;4种方案人均查病费用分别为6.83、7.06、7.33元和7.62元。DDIA、ELISA筛查时分别漏检病人1例和2例;Kato-Katz、集卵孵化法分别漏检病人9例和3例,漏检率为31.03%和10.34%。结论 DDIA+集卵孵化法或ELISA+集卵孵化法均可作为血吸虫病疫情控制地区的查病方案,但DDIA+集卵孵化法更有效、经济。Objective To explore the suitable scheme of field screening in transmission-controlled areas of schistosomiasis. Methods According to the principle of single blind, a sample of 6-65 age old people were selected and examined by different schemes including dipstick dye immunoassay (DDIA) plus Kato-Katz method, DDIA plus stool hatching method, enzyme-linked immunosorbent assay (ELISA) plus Kato-Katz method, and ELISA plus stool hatching method, and the reason of missing examination was analysed, and the missing rate and costs of the different schemes were campared. Results A total of 1 251 residents from Yanjiang Village were examined, the acceptance rate was 92.19% (1 251/1 357), and the cases of serum-positive and stool-positive were 298 and 29, respectively. The cases of stool-positive identified by DDIA plus Kato-Katz, DDIA plus stool hatching method, ELISA plus Kato-Katz method and ELISA plus stool hatching method were 19, 26, 19 and 24 respectively, the missing cases were 10, 3, 10 and 5, the missing rates were 34.48%, 10. 34%, 34.48% and 17.24% , the average examination costs were 6.83, 7.06, 7.33, and 7.62 Yuan. The missing cases of DDIA and ELISA were 1 and 2, respectively. The missing cases and rates of Kato-Katz and stool hatching method were 9, 3 and 31.03%, 10.34% respectively. Conclusions The scheme of DDIA or ELISA plus stool hatching method can be used in transmission-controlled areas, but the scheme of DDIA plus stool hatching method is more efficient and economic.

关 键 词:血吸虫病 DDIA ELISA 集卵孵化法 Kato-Katz 疫情控制地区 查病方案 

分 类 号:R532.21[医药卫生—内科学]

 

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