慢性丙型肝炎患者血清HA、PCⅢ和ADA检测的临床意义  

Clinical Significance of Determination of Serum HA,PCⅢ and ADA Levels in Patients with Chronic Hepatitis C

作　　者：张晶[1] 于帆[1] 赵长新[1] 

机构地区：[1]江苏省连云港市第二人民医院感染科,222023

出　　处：《放射免疫学杂志》2006年第4期296-297,共2页Journal of Radioimmanology

摘　　要：目的:探讨了慢性丙型肝炎患者血清HA、PCⅢ和ADA水平的变化。方法:应用放射免疫分析测定了42例慢性丙型肝炎患者血清中HA、PCⅢ和ADA含量,并与35名健康人作比较。结果:慢性丙型肝炎患者血清中HA、PCⅢ和ADA含量非常显著地高于正常人组(P<0.01),且呈明显的正相关(r=0.6178、0.6211,P<0.01)。结论:检测慢性丙型肝炎患者血清HA、PCⅢ和ADA是反映慢性丙型肝炎患者肝功能损害程度的指标之一,可用于判断慢性丙型肝炎患者肝功能损害程度及评价预后。Objective To explore the changes of serum HA, PCⅢ and ADA levels in patients with chronic hepatitis C. Methods Serum HA, PC Ⅲ and ADA levels were detected with RIA in 42 cases with chronic hepatitis C and 35 controls. Results Thelevels of serum HA, PC Ⅲ and ADA in the patients were significantly higher than those in controls （ P 〈 0.01 ）. Serum HA, PCⅢ and ADA levels were positive correlated （r = 0. 6178, 0. 6211, P 〈 0.01 ）. Conclusion The results suggested the serum HA, PC Ⅲ and ADA levels can reflect the degree of hepatic injury in the patients with cirrhosis, detection of serum HA, PC Ⅲ and ADA levels is helpful in estimating the status of the disease.

关 键 词：慢性丙型肝炎 透明质酸 Ⅲ型前胶原 腺苷脱氨酶 

分 类 号：R512.63[医药卫生—内科学]