脂质沉积性肌病的MRI诊断  

Diagnosis of MRI in lipid storage myopathy

作　　者：郑贤应[1] 慕容慎行[1] 李银官[1] 倪希和[1] 曹代荣[1] 

机构地区：[1]福建医科大学附属第一医院,福建福州350005

出　　处：《中国临床医学影像杂志》2006年第8期458-460,共3页Journal of China Clinic Medical Imaging

摘　　要：目的:研究脂质沉积性肌病(LSM)的MRI表现,并评价MRI在LSM诊断中的应用价值。材料和方法:选择骨盆及双侧大腿肌肉,对9例LSM患者行MRI检查,采用自旋回波序列(SE)、快速自旋回波序列(FSE)及短时反转恢复序列(STIR)。结果:8例LSM患者的受累肌群均表现为片状短T1长T2异常信号,以臀肌及大腿后肌群受累为主,2例活动期患者的病变肌肉中尚混杂有斑片状长T1长T2异常信号影;1例无阳性表现。结论:LSM的MRI表现具有一定的特征性,受累肌群主要表现为脂肪沉积改变,在活动期,肌纤维可见斑片状坏死信号,病变双侧对称;MRI能为LSM的诊断、疗效判断及病情随访提供客观资料,并能为临床选取准确的活检部位提供定位。Objective： To investigate MRI findings of lipid storage myopathy（LSM）, and evaluate the clinical value of MRI for LSM. Materials and Methods： Nine cases with LSM proved by biopsy underwent MRI of pelvis and thigh, spin echo sequence, fast spin echo sequence and short tau inversion recovery（STIR） were used. Results： The signal intensity of diseased muscle in 8 cases with LSM was hyperintense on T2WI and T1WI, and hyperintense signal intensity on T2WI and iso-intense on T1WI was seen on 2 patients as well. One patient had no positive findings. Conclusion： The MRI findings in LSM show certain characteristics： the involved muscles show lipid storage findings symmetrically, and the necrotic-like signal can be seen in the active stage as well. MRI can provide objective data for clinical diagnosis, therapeutic evaluation and follow-up. It can also help to decide the accurate site for biopsy.

关 键 词：肌疾病 磁共振成像 

分 类 号：R685[医药卫生—骨科学] R445.2[医药卫生—外科学]