依地红皮肤消毒剂对皮肤刺激性的实验研究  

The experimental study on the skin irritation of Yidihong disinfectant

作　　者：刘玉明[1] 靳小青[1] 黄宝康[2] 沈越[1] 吴苏舒[1] 

机构地区：[1]海军医学研究所新药研究中心,上海200433 [2]第二军医大学药学院,上海200433

出　　处：《中医药导报》2006年第8期18-19,共2页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：中国人民解放军海军医学研究所青年基金资助(05HY061)

摘　　要：目的:探讨依地红皮肤消毒剂对皮肤的刺激作用,并进行安全性评价。方法:制备依地红皮肤消毒剂,用皮肤刺激反应评分表,评价该药对豚鼠的皮肤刺激反应。结果:单次涂药时,对完整皮肤组和破损皮肤组均无刺激性;多次涂药皮肤刺激实验中,对于破损皮肤有轻度刺激性。结论:依地红皮肤消毒剂对皮肤具有较高的安全性。Objective： To explore the guinea pigs＇skin irritation of Yidihong disinfectant was performed for safety assessment. Methods ： Use the response table to assess the guinea pigs＇ skin irritation of Yidihong disinfectant. Results Single application of Yidihong disinfectant produce no irritation to the integrity or damaged skin of guinea pig. Slight irritation on the integrity or damaged skin of guinea pig was observed on condition of sequential application of Yidihong disinfectant. Conclusion： Yidihong disinfectant was safe and showed no irritation to guinea pigs＇ skin.

关 键 词：依地红 消毒剂 皮肤刺激性 

分 类 号：R285.5[医药卫生—中药学]