氮杂冠醚取代非对称双Schiff碱配合物催化羧酸酯水解的动力学研究  

The Study on Aza Crown Ether Substituted Asymmetry Bis-Schiff Base Complexes for PNPP Ctalytic Hydrolysis

作　　者：谢斌[1] 蒋维东[1] 李建章[1] 李志成[1] 王莹[1] 徐斌[1] 秦圣英[2] 

机构地区：[1]四川理工学院化学系绿色化学重点实验室,四川自贡643000 [2]四川大学化学学院,成都610064

出　　处：《四川大学学报（自然科学版）》2006年第4期872-877,共6页Journal of Sichuan University(Natural Science Edition)

基　　金：四川省教育厅重点专项基金(2005D007);国家自然科学基金(20072025)

摘　　要：将4种氮杂冠醚取代非对称双Schiff钴(II)、锰(III)配合物作为仿水解酶模型催化羧酸酯(PNPP)水解.探讨了Schiff配合物催化PNPP水解的动力学和机理;提出了配合物催化PNPP水解的动力学模型.结果表明,在25℃条件下随着缓冲溶液pH值的增大,配合物催化PNPP水解速率提高,并表现出好的催化活性.Four aza crown ether substituted asymmetry bis-Schiff base transition-mental complexes was used as mimic hydrolytic enzyme model for catalyzing carboxylic acid esters （PNPP） hydrolysis. The kinetics on PNPP hydrolysis catalyzed by these complexes has been investigated. The kinetic mathematical model of PNPP cleavage catalyzed by these complexes has been proposed. The results showed that the rate for the catalytic PNPP hydrolysis is increased following the increase of pH of the buffer solution; four complexes exhibit high activity in the catalytic PNPP hydrolysis.

关 键 词：氮杂冠醚 非对称双Schiff碱 过渡金属配合物 PNPP水解 动力学 

分 类 号：O614.81[理学—无机化学]