类风湿因子检测中乳胶凝集试验与散射比浊法的对比研究  

Comparison of latex agglutination test and turbidimetric assay for rheumatoid factor

作　　者：孙丽丽[1] 

机构地区：[1]江苏省南通市中医院,江苏南通226001

出　　处：《现代中西医结合杂志》2006年第17期2320-2321,共2页Modern Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的国内常用检测类风湿因子(RF)的方法有散射比浊法和乳胶凝集试验。笔者对散射比浊法和乳胶凝集试验的相关性进行了对比研究。方法对133例门诊及住院患者血清标本同时采用乳胶法和比浊法进行类风湿因子检测,并对测得的数据进行统计学处理。结果散射比浊法、乳胶凝集法测定RF阳性率分别为15.0%和11.2%,前者与后者有显著性差异(P<0.05),测定血清中RF的水平,散射比浊法比乳胶凝集法更敏感。结论对散射比浊法和乳胶凝集试验进行对比研究后发现,散射比浊法优于乳胶凝集法。Objective Usual methods of rheumatoid factor （RF） include turbidimetric assay and latex agglutination test. This study was aimed to compare the relativity of the two methods. Methods Tests for rheumatoid factor were performed by the two methods among the outpatients and inpatients in the hospital. Results The rates of the turbidimetric assay and latex agglutination test were 15.0% and 11.2 % respectively. Measuring the level of RF in serum, there was significant difference between the two methods（ P 〈 0.05 ）, and turbidimetric assay was more sensitive than latex agglutination. Conclusion Compared with the latex agglutination test, turbidimetric assay was more excellent.

关 键 词：类风湿因子 散射比浊法 乳胶凝集试验 

分 类 号：R446.61[医药卫生—诊断学]