水蛭土元粉联用硝苯吡啶治疗高血压并左室肥厚的临床研究  

Clinical Study on Combined Treatment of Shuizhi Tuyuan Powder and Nifedipine in Treating Hypertension Patients Complicated with Left Ventricular Hyhertrophy

作　　者：魏爱英[1] 李运乾 陈健夫 王达平[1] 魏丽英[1] 

机构地区：[1]解放军第264医院,山西省心血管病研究所

出　　处：《中国中西医结合杂志》1996年第11期652-654,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：本研究选择经超声心动图检查有左室肥厚（ＬＶＨ）的高血压病患者，随机分为观察组和对照组。两组均给予硝苯吡啶治疗，观察组加用水蛭土元粉胶囊。结果表明：观察组心肌重量指数（ＬＶＭＩ）由１３６．８±７．５ｇ／ｍ￣２降至１３０．５±６．４ｇ／ｍ￣２，部分有早期脑血管病症状的患者症状改善。对照组ＬＶＭＩ由１３６．７±７．４ｇ／ｍ￣２降至１３４．３±６．２ｇ／ｍ￣２。两组治疗后比较有显著性差异（Ｐ＜０．０１）。提示水蛭土元粉联用硝苯吡啶对高血压并ＬＶＨ及部分有早期脑血管病症状的患者有积极的治疗作用。Patients with essential hypertension complicated with left ventricular hypertrophy(LVH) confirmed by ultrasonic cardiography were divided randomly into observation group and control group. Both groups were treated with nifedipine.Shuizhi Tuyuan Powder(SZTYP,consisted of Hirudo nipponia and Eupolyphaga sinensis) was given in addition to the observation group. The therapeutic course for the two groups were 6 months. Results showed that after one course of treatment, the myocardial weight index lowered from 136.8±7.5 g/m2 to 130.5±6. 4 g/m2 in observation group, while in control group,it lowered from 136.7± 7.4 g/m2 to 134.3±6.2 g/m2, the difference between the two groups was significant(P<0.01).The symptoms were relieved in part of the patients with early stage of cerebrovascular disease treated with SZTYP. The results suggested that SZTYP combined with nifedipine has active curative effect on essential hypertension patients complicated by LVH and part patients in early stage of cerebrovascular disease.

关 键 词：水蛭土元粉 硝苯吡啶 高血压 左室肥厚 

分 类 号：R259.441[医药卫生—中西医结合]