补肾活血中药治疗中老年女性甲亢患者骨代谢紊乱的临床研究  

A Study on Observation of Bone Metabolism in Middle-aged and Senile Female Graves' Disease

作　　者：朱立群[1] 刘英华[1] 周荫保[1] 卢倜章[1] 

机构地区：[1]天津医科大学内分泌研究所,天津市和平区中医医院

出　　处：《中国中西医结合杂志》1996年第8期467-469,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：本研究对有骨代谢紊乱的中老年女性甲亢患者分组进行了传统西药及中西医结合治疗观察。治疗前，两组血Ｃａ（Ｃａ）及２４ｈ尿Ｃａ（Ｕ－Ｃａ）、尿Ｐ（Ｕ－ｐ）水平及血清降钙素水平均明显高于正常。患者血清Ｔ３与血Ｃａ水平呈正相关（ｒ＝０．６１４２，Ｐ＜０．０１），血Ｃａ与降钙素水平也呈正相关（ｒ＝０．５７１４，Ｐ＜０．０５）。治疗后，两组血Ｃａ及２４ｈＵ－Ｃａ、Ｕ－Ｐ及血清降钙素水平均有下降，但以中西医结合治疗的Ｂ组下降更明显。观察结果表明，对于中老年女性甲亢患者在用他巴唑等抗甲状腺药物治疗的同时采用补肾活血中药进行中西医结合治疗，可以有效地防止患者骨质丢失。Sixty-nine cases of middle aged and senile female Graves'desease(GD) patients suffered from abnormal bone metabolism have been studied. They were divided randomly into group A and B,treated separately with antithyroid drugs(Tapazol and inderal, etc.) in group A, and added with Chinese herbal medicine for tonifying Kidney and promoting blood circulation in group B. Before treatment, patients of both groups showed obvious higher blood calcium(Ca) 24-hour urinary Ca,phosphorus(P) and serum clcitonin(CT) levels than that in normal subjects. These patients'serum Ca, moreover, had a parallel relationship with serum T_3 levels(r= 0 . 6142, P <0 . 01) and the serum Ca also a parallelled with serum CT levels(r=0. 5714, P <0.05). After six months of treatment,the serum Ca, 24-hour urinary Ca, P and blood CT values were all reduced in various degree. The decrease of these bone metabolic parameters were more significant in group B than that in group A.

关 键 词：补肾活血 女性 甲亢 骨代谢紊乱 中医药疗法 

分 类 号：R259.811[医药卫生—中西医结合]