胸腹水LDH和与血清LDH比值及TP测定的临床鉴别诊断价值  

Clinical Differential Diagnostic Value of LDH and Proportion of LDH and TP in Benign and Malignant Hydrothorax and Hydroperitoneum

作　　者：张淑艳[1] 王北宁[1] 

机构地区：[1]北京军区总医院检验科,北京100700

出　　处：《华北国防医药》2006年第4期276-277,共2页Medical Journal of Beijing Military Region

摘　　要：目的:探讨胸腹水中的乳酸脱氢酶(LDH)和胸腹水中的LDH与血清LDH的比值及总蛋白(TP)测定的临床鉴别诊断意义。方法:分别采用乳酸法和双缩脲比色法检测73例患者不同性质胸腹水中的LDH和与血清LDH比值及TP的浓度,并对检测数据进行统计分析。结果:恶性肿瘤组和结核性胸膜炎组标本胸腹水LDH差异无显著性(P>0.05),但均高于慢性非特异性炎症组(P<0.05);恶性肿瘤组和慢性非特异性炎症组的胸腹水LDH与血清LDH比值差异无显著性(P>0.05),但均高于结核性胸膜炎组(P<0.05);恶性肿瘤组和结核性胸膜炎组标本TP差异无显著性(P>0.05),但均高于慢性非特异性炎症组(P<0.05)。结论:联合检测胸腹水LDH和胸腹水LDH与血清LDH比值及TP对胸腹水的鉴别诊断有重要的临床参考价值。Objective：To discuss the clinical differential diagnostic significance of lactate dehyrogenase （LDH） and proportion of LDH and protein （TP） in benign and malignant hydrothorax and hydroperitoneum. Methods：Lactic acid and biuret were used to determine the concentrations of LDH , proportion of LDH and TP in different samples of hydrothorax and hydroperitoneum from 73 patients, respectively . The results were statistically analyzed. Results ：The LDH values in the samples from the malignant tumour patients and the tuberculous pleuritis patients did not show significant difference （ P 〉 0. 05 ）, but were higher than that from the chronic nonspecific inflammation patients （ P 〈 0. 05 ）. The proportion of LDH in the samples from the malignant tumor patients and the chronic nonspecific inflammation patients were similar （ P 〉 0. 05 ） but higher than that from the tuberculous pleuritis patients （ P 〈 0. 05 ）. The TP values in the samples from the malignant tumour patients and the tuberculous pleuritis patients were similar （ P 〉 0. 05 ）, but higher than that from the chronic nonspecific inflammation patients （P 〈 0. 05 ）. Conclusion ：The combined method of detection of LDH and the proportion of LDH and TP have shown important clinical reference value in differential diagnosis of hydrothorax and hydroperitoneum quality.

关 键 词：胸腔积液 腹水 乳酸脱氢酶 总蛋白 

分 类 号：R446.1[医药卫生—诊断学]