阴道加德纳菌感染与男性不育的相关性研究  

Gardnerella vaginalis and Male Infertility

作　　者：楚雅玲[1] 岳林[2] 王丽芬[2] 陈淑敏[2] 

机构地区：[1]河南科技大学第一附属医院,河南洛阳471003 [2]洛阳市中心医院,河南洛阳471009

出　　处：《中华医院感染学杂志》2006年第8期889-890,共2页Chinese Journal of Nosocomiology

摘　　要：目的探讨精液中阴道加德纳菌(Gv)感染与男性不育的关系。方法采用套式PCR术进行Gv检测并与精液参数、精液白细胞含量、AsAb进行相关分析;383例男性不育就诊者精液中检出Gv阳性者设为阳性组;精液Gv阴性者设为阴性组。结果就诊者精液中检出Gv阳性者86例,阳性组精子密度、精子活率、a+b活力、低渗肿胀率明显低于阴性组(P<0.05);而阳性组精子畸形率、精液pH值,白细胞精液症检出率、AsAb阳性率明显高于阴性组(P<0.05,P<0.01);两组精液量、精液黏度增高率差异无显著性(P>0.05)。结论精液中Gv感染可影响精液质量,是男性不育的重要原因之一。OBJECTIVE To study the relationship between Gardnerella vaginalis and male infertility. METHODS To test G. vaginalis in semen by nested PCR and to carry out correlation analysis with sperm parameter, volumetric count of leukocytes and AsAb. Totally 383 male cases with infertility, set up into positive group, other 297 cases set up into negative group. RESULTS G. vaginalis in semen was positive in 86 cases in positive group, their semen concentration, motility, a＋b grade motile, and the swelling rate of hypoosmotic swelling test were observed to be evidently lower compared to negative group（P〈0.05）. In addition, higher abnormal morphological sperm and pH value, increased volumetric count of leukocytes and positive AsAb rate were observed in positive group（P〈0.05, P〈0.01）. Sperm volume and semen viscosity rate were without difference between positive group and negative one（P〉0.05）. CONCLUSIONS G. vaginalis has an effect on sperm quality.

关 键 词：阴道加德纳菌 聚合酶链反应 精液参数 男性不育 

分 类 号：R698.2[医药卫生—泌尿科学]