间苯三酚配伍异丙酚用于无痛人工流产术的临床评价  

Clinical Evaluation of Spasfon Used as Analgesia in Surgical Abortion

作　　者：公文华[1] 王雪芹[1] 张鹏[1] 

机构地区：[1]山东大学齐鲁医院,山东济南250012

出　　处：《实用妇产科杂志》2006年第8期496-498,共3页Journal of Practical Obstetrics and Gynecology

摘　　要：目的：探讨间苯三酚配伍异丙酚用于无痛人工流产术的效果及安全性。方法：我院2004年2～12月自愿实行无痛人工流产术者随机分成两组：间苯三酚组20例和芬太尼组20例。在麻醉诱导前10分钟，间苯三酚组静脉注射间苯三酚40～80mg；芬太尼组注射芬太尼1μg／kg。然后以异丙酚1．5～2．5mg／kg麻醉诱导，术中异丙酚麻醉维持。比较两组的效果及不良反应。结果：间苯三酚对人工流产手术引起的疼痛的止痛效果优于芬太尼（P〈0．05），对呼吸的抑制作用较轻（P〈0．05）；无不良反应，不影响术后苏醒，也不会增加术后阴道流血量，无一例并发症发生。结论：间苯三酚与异丙酚配伍用于无痛人工流产术效果好，不良反应小，安全性高，值得推荐。Objective. To study the effect and safety of Spasfon or Fentany combined Propofol for analgesia in induced abortion. Methods：To randomly separate the pregnant women who have been voluntarily carried out the induced abortion of indolence from February 2004 to December 2004 in our hospital into two groups： Spasfon group（ n = 20）and Fentany group（n =20）.Ten minutes before anesthesia induction,40-80 mg Spasfon and 1 1μg/kg Fentany was given via vein in Spasfon group and Fentany group, separately. Then the patients in two groups were induced with 1.5 -2.5 mg/kg Propofol, and maintained anesthesia with Propofol by infusion pump. The anesthesia effect and side reaction were compared between two groups.Results：The analgesic efficacy of Spasfon plus Propofol was better than that of Fenteny plus Propofol （ P 〈 0. 05）. The prevalence of respiratory suppression in Spasfon group was significantly lower than Fentany group （ P〈 0.05） .There was no side effect without increment of post-operational bleeding and any influence on patients＇ revitalization. No of case occurred complication pari- and post-operation. Conclusions： Spasfon plus Propofol used as anesthesia in induced abortion can provide better analgesic efficacy.fewer side-effect,and higher safety.

关 键 词：间苯三酚 芬太尼 异丙酚 无痛人工流产术 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]