二乙基二硫代氨基甲酸银法测定3种中药制剂中微量砷  

Determination of trace arsenic with silver diethyldithiocarbamate method in 3 traditional Chinese medicine preparations

作　　者：王守愚[1] 张文洁 赵清 王茂训 

机构地区：[1]辽宁中医学院,沈阳110032 [2]辽宁省中药研究所,沈阳110161 [3]辽宁电力中心医院,沈阳110015

出　　处：《药物分析杂志》2006年第7期1021-1022,共2页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:对清金利咽茶、附子理中丸、板蓝根冲剂中微量砷含量进行准确测定。方法:采用二乙基二硫代氨基甲酸银(Ag-DDC)比色法测定中药制剂中微量砷。结果:本法灵敏度高、重现性好,砷浓度在0.06451～0.1935μg·mL^(-1)范围内,与吸收度呈良好的线性关系。清金利咽茶、附子理中丸、板蓝根冲剂中砷含量在0.5～3μg·g^(-1)之间。结论:清金利咽茶砷含量超标,附子理中丸、板蓝根冲剂中砷含量合格。Objective：To determine accurately the content of trace arsenic（As） in Qinjinliyan tea, Fuzilizhong pills and Banlangen granulation. Methods： Silver diethyldithioearbamate （ Ag - DDC ） method was used to determine the arsenic of traditional Chinese medicine preparation. Results：This method had high sensitivity and good reappearanee. In the range of 0. 06451 -0. 1935 μg · mL^-1 , the concentration of As and the absorption had good linear relations. The content of As of above medicines is among 0. 5 and 3 μg · g^-1. Conclusion：The content of As in Qinjinliyan tea exceeded quota, and the content of As in Fuzilizhong pills and Banlangen granulation reach standard.

关 键 词：二乙基二硫代氨基甲酸银(Ag-DDC)法 清金利咽茶 附子理中丸 板蓝根冲剂 砷 

分 类 号：R917[医药卫生—药物分析学]