抗球虫药癸氧喹酯的合成  

Synthesis of Coccidiostat Decoquinate

作　　者：彭志强 

机构地区：[1]广东省天宝生物制药有限公司,广东广州510655

出　　处：《中国兽药杂志》2006年第8期21-22,共2页Chinese Journal of Veterinary Drug

摘　　要：癸氧喹酯(Decoquinate)为抗球虫新药,国外主要以对硝基愈创木醚钾或对硝基儿茶酚钠等为原料制得。本文采用国内已工业化生产的邻羟基苯乙醚为原料,通过硝化、还原及高温缩合等反应顺利制得该产品。Decoquinate is a new coccidiostat which was synthesized from potassium p-nitroguaiacoxide or 4-nitrocatechol mono-sodium salt at abroad. In this study, with home-made 2-ethoxyphenol as raw material, decoquinate was synthesized by nitration, reduction and high-heat condensation reaction.

关 键 词：抗球虫新药 癸氧喹酯 邻羟基苯乙醚 合成工艺 

分 类 号：TQ460.6[化学工程—制药化工]