糖尿病非酮症高渗综合征148例临床分析  

Clinical analysis of 148 cases of diabetic nonketotic hyperosmolar syndrome

作　　者：蒋建家[1] 苏劲波[1] 吴东熹[1] 

机构地区：[1]泉州市第一医院,362000

出　　处：《福建医药杂志》2006年第4期18-20,共3页Fujian Medical Journal

摘　　要：目的分析糖尿病非酮症高渗综合征(DNHS)的诱因和与之相关的病死率,探讨急性心脑血管意外诱发的DNHS的合理治疗。方法回顾分析2001年1月至2005年10月在我院住院的148例DNHS的诱因及血浆渗透压、补液速度、降糖速度指标,并与同期住院的非DNHS糖尿病合并急性心梗和急性脑血管意外的病死率进行比较。结果DNHS患者中诱因为急性感染的44例(29.7%),脑血管意外37例(25.0%),急性心肌梗死26例(17.6%)。后两组的病死率,与对应的非DNHS糖尿病合并急性心梗组和脑血管意外组的病死率比较无显著性差异。DNHS患者心脑血管诱因组病死率与非心脑血管诱因组比较无显著性差异(P>0.05)。结论急性心脑血管意外已逐渐取代急性感染成为DNHS的主要诱因。适当的补液速度可提高急性心脑血管病诱发的DNHS的抢救成功率。Objective To analyze precipitating factors of diabetic nonketotic hyperosmolar syndrome （DNHS） and its correlative mortality, and discuss the reasonable treatment of DNHS caused by the cardiocerebrovascular attack. Methods The inducement, osmolarity, speed of injecting fluid and decreasing blood glucose of 148 patients with DNHS being in our hospital from January 2001 to October 2005 were reviewed and analyzed. The motality of DNHS patients was compared with that non- DNHS diabetes with acute myocardial infarction and cerebrovascular attack, being in the hospital at the same time. Results There were 44 cases （29.7%） caused by acute infection in DNHS group. 37 cases （25.0%） caused by cerebrovascular attack, and 26 cases （17.6%） caused by acute myocardial infarction. The motality of the other two interns had not separately prominent difference to the non-DNHS diabetes with acute myocardial infarction and cerebrovascular attack. The mortality of DNHS patients caused by cardiocerebrovascular attack had not prominent difference to the non-cardiocerebrovascular attack （P〉0.05）. Conclusion Acute cardiocerebrovascular attack has replaced acute infection and became the most primary precipitating factor of DNHS. Proper speed of injecting fluid can improve successful rate of saving DNHS caused by acute cardiocerebrovascular disease.

关 键 词：糖尿病非酮症高渗综合征 心脑血管意外 

分 类 号：R587.2[医药卫生—内分泌]