鲜鱼腥草的黄酮类化合物研究  

Study on chemical constituents of flavonoids in fresh herb of Houttuynia cordata

作　　者：孟江[1] 董晓萍[2] 姜志宏[1] 梁士贤[1] 赵中振[1] 

机构地区：[1]香港浸会大学中医药学院 [2]成都中医药大学药学院,四川成都610081

出　　处：《中国中药杂志》2006年第16期1335-1337,共3页China Journal of Chinese Materia Medica

摘　　要：目的:研究三白草科Saururaceae蕺菜属植物蕺菜Houttuynia cordata的黄酮类化学成分。方法:利用Diaion HP-20,Sephadex LH-20,ODS和硅胶柱色谱进行分离纯化,根据化合物的理化性质和光谱数据鉴定结构。结果:分离得到5个化合物,分别鉴定为槲皮素-3-O--βD-半乳糖-7-O--βD-葡萄糖苷(1),山柰酚-3-O--βD-[-αL-吡喃鼠李糖(1→6)]吡喃葡萄糖苷(2),槲皮苷(3),金丝桃苷(4),槲皮素-3-O--αD-鼠李糖-7-O--βD-葡萄糖苷(5)。结论:化合物1,2,5为首次从该属及本植物中分离得到。Objective： To study the flavonoid constituents in fresh herb of Houttuynia cordata. Method： Various column packing materials ineluding; Diaion HP- 20, Sephadex Lid - 20, ODS and sifiea gel were employed for the isolation and purification of compounds from H. cordata. The structures of the compounds were identified by physiochemical properties and spectral analysis. Result： Five compounds were isolated, and their structures were identified as quercetin-3- O-β-D-galactoside-7- O-β-D-glucoside （1）, kaempferol-3- O-α-L-rhamnopyranosyl- （ 1→6）-β-D-glueopyranoside （2）, quercitrin （3）, hyperin （4）, quercetin 3- O-α-L-rbamnopyranosyl-7- O-β-D-glueopyranoside （5）. Conclusion： Compounds 1, 2 and 5 were separated from H. cordata for the first time.

关 键 词：鲜鱼腥草 化学成分 黄酮类 

分 类 号：R284.1[医药卫生—中药学]