中老年高级知识分子1060人体脂分布类型与心血管病危险因素水平及聚集程度的关系  

Correlation of body fat distribution pattern with cardiovascular risk factors and their clustering in 1060 middle-to-elderly aged senior intellectuals

作　　者：祁双宝[1] 成守金[1] 许风清[1] 

机构地区：[1]河南省焦作煤业集团公司中央医院检验科,河南省焦作市454000

出　　处：《中国临床康复》2006年第36期7-9,共3页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:调查焦作煤业集团公司45岁以上高级知识分子体脂分布类型与心血管病危险因素水平及危险因素聚集程度的关系。方法:于2005-07-01/09-30对焦作煤业集团45岁以上具有高级职称(高级工程师、主任医师、教授)的知识分子1060人进行调查分析。按照北京阜外医院心血管流行病研究室统一设计的规格进行调查与统计,测量并记录调查对象的年龄、性别、身高、体质量、腰围、收缩压、舒张压,并计算体质量指数。体质量指数=体质量(kg)/身高(m2),根据腰围和体质量指数将调查对象体脂分布类型划分为外周型非超重组、外周型超重组、中心型非超重组、中心型超重组4组。调查对象空腹12h抽取静脉血,采用AU640全自动生化分析仪测量其血清中总胆固醇、三酰甘油、空腹血糖、高密度脂蛋白胆固醇。结果:纳入调查对象1060人,均进入结果分析,男764人,平均年龄(56.1±7.8)岁,女296人,平均年龄(54.5±9.2)岁。①不同体脂分布人群心血管危险因素水平比较:血压、总胆固醇、三酰甘油、空腹血糖以及危险因素聚集程度中心型超重组明显高于外周型非超重组和外周型超重组(t=2.35～9.67,P<0.05～0.01)d中心型非超重组、中心型超重组的高密度脂蛋白胆固醇低于外周型非超重组(t=2.49～9.67,P<0.05～0.01)。②不同体脂分布人群的心血管病危险因素检出率及其危险因素聚集程度结果分析:即使同在非超重组,中心型非超重组的2,3,4级危险因素聚集程度也明显高于外周型非超重组(χ2=58.58,25.63,19.56,P均<0.01)。③体脂分布类型比较:男性人群外周型非超重组、外周型超重组、中心型非超重组、中心型超重组体脂分布类型所占比例分别为8.6%,25.6%,29.7%,36.1%,女性人群外周型非超重组、外周型超重组、中心型非超重组、中心型超重组体脂分布类型所占比例分别为35.2%,24.1%,23.8%,16.9%。④不同性别人群AIM： To study the relation of body fat distribution （BFD） pattern with cardiovascular risk factor （CRF） and their clustering in the senior intellectuals aged over 45 years from Jiaozuo Coal Co., Ltd. METHODS： The survey was carried out in the 1 060 intellectuals with senior titles （senior engineer, attending physician or professor）, aged over 45 years from Jiaozuo Coal Co., Ltd. between July 14 and September 30^th 2005. With the uniform standard devised by Department for Cardiovascular Epidemiology, Beijing Fuwai Hospital, the date on age, gender, body height, body mass, waist circumference （WC）, systolic blood pressure （SBP）, diastolic blood pressure （DBP） were measured and recorded . The body mass index （BMI） was calculated as body mass （kg）/body height （m^2）. According toWC and BMI, the BFD patterns were divided into 4 groups： peripheral non-overweight group, peripheral overweight group, central nonoverweight group and central overweight group. The venous bloods were collected after 12-hour fasting, and total cholesterol （TC）, triglyceride （TG）, high-density lipoprotein cholesterol （HDL-C） and fasting blood sugar （FBS） were detected with AU640 automatic biochemistry analyzer. RESULTS： A total of 1 060 subjects were involved in the result analysis, including 764 males mean aged （56.1 ±7.8） years and 296 females mean aged （54.5±9.2） years. ①Comparison of CRF levels in people with different BFDs： SBP, DBP, TC, TG, FBS and clustering level of CRF were markedly higher in central overweight group than in peripheral non-overweight group and peripheral overweight group （t=2.35-9.67,P 〈 0.05-0.01）; Whereas HDL-C were lower in the central non-overweight group and central overweight group than in the peripheral non-overweight group （t=2.49-9.67, P 〈 0.05-0.01）. ②Detection rates and clustering level of CRF in people with different BFDs： The clustering levels of CRF at Grade 2,3,4 were markedly higher in the central non-overweight gro

关 键 词：心血管疾病 危险因素 流行病学 

分 类 号：R714.252[医药卫生—妇产科学]