冠心病合并2型糖尿病患者冠状动脉病变严重程度的研究  

Comparison of the severity and extent of the coronary artery disease between patients with and without type-2 diabetes mellitus

作　　者：容志毅[1] 张小红[1] 刘向儒[1] 王仲华[1] 

机构地区：[1]郴州市第一人民医院,湖南郴州423000

出　　处：《心血管康复医学杂志》2006年第4期324-326,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:探讨2型糖尿病与冠状动脉病变严重程度的关系。方法:对象为选择性冠状动脉造影确诊的冠心病患者266例,其中合并2型糖尿病者96例,无糖尿病者170例。计算冠脉病变支数和进行Gensini冠脉病变评分。结果:冠心病合并2型糖尿病患者的冠脉病变Gensini评分和三支病变者明显多于不合并2型糖尿病的冠心病患者(P<0.05);简单直线相关分析表明,甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、体重指数等与冠状动脉病变严重程度显著相关(P均<0.01)。结论:冠心病患者合并2型糖尿病将加重冠状动脉病变严重程度。Objective ： To explore the relationship between the type- 2 diabetes mellitus （DM） and the severity and extent of coronary artery disease. Methods： A total of 296 coronary heart disease （CHD） patients identified by the coronary angiography were included in the study. Of which 96 with type-2 DM and 170 without. The number of the diseased coronary arteries and the Gensini＇s score were calculated. Results： The Gensini＇s score and percentage of threebranch lesion of with type-2 diabetes group were higher than those of patient without DM （P〈0.01）. Simple correlation analysis indicated that the severity of the coronary artery disease was significantly correlated with the TG. TC. HDL-C, LDL-C and the body mass index （P〈0. 01 all）. Conclusion： Coronary aryery disease complicated diabetes mellitus may aggravate the severity of coronary artery disease.

关 键 词：糖尿病 2型 冠状动脉疾病 冠状血管造影术 

分 类 号：R541.409[医药卫生—心血管疾病]