CD44V6在鼻咽癌IL-2治疗前后的表达意义  

EXPRESSION AND SIGNIFICANCE OF CD44V6 IN NASOPHARYNGEAL CARCINOMA BEFORE AND AFTER IL-2 THERAPY

作　　者：王薇[1] 孙学威[1] 诸小侬[2] 

机构地区：[1]内蒙古医学院附属医院耳鼻咽喉科,内蒙古呼和浩特010050 [2]北京市耳鼻咽喉研究所

出　　处：《内蒙古医学院学报》2006年第4期276-278,共3页Acta Academiae Medicinae Neimongol

摘　　要：目的:探讨CD44V6在鼻咽癌IL-2治疗前后表达的意义。方法:两组鼻咽病人者分别进行IL-2局部和全身免疫治疗,用免疫组化方法检测CD44V6的表达。结果:两组中CD44V6表达有显著差异(P<0.05)。结论:与全身应用相比,局部应用IL-2可降低鼻咽癌组织的淋巴结转移潜能。Objective：To study the expression and significance of CIM4V6 in nasopharyngeal carcinoma （NPC） before and after IL- 2 therapy. Methods： Two group NPC patients were treated respectively by IL -2 local or whole immunization therapy. To examine the expression of CD44V6 with immunohistochemistry. Results ：The two group expression of CD44V6 have significant difference （P 〈 0.05）. Conclusion：To compare with the whole treatment, the local applyment may reduce the lymphatic node metastasis latent energy.in NPC.

关 键 词：鼻咽癌 CD44V6 白细胞介素Ⅱ免疫治疗 

分 类 号：R766.3[医药卫生—耳鼻咽喉科]