倍他米松二甲基亚砜酊中倍他米松的含量测定  

Determination of Betamethason in Betamethason Tincture by Spectrophotometric Method

作　　者：陈玲玲[1] 张春泉[1] 杜利萍[1] 

机构地区：[1]浙江医院药剂科,浙江杭州310013

出　　处：《中国药业》2006年第14期14-14,共1页China Pharmaceuticals

摘　　要：目的建立倍他米松酊的含量测定方法。方法通过水浴蒸干排除二甲基亚砜的干扰,用紫外分光光度法测定倍他米松的含量。结果倍他米松浓度在3.0～36.0μg m/L范围内与吸收度有良好的线性关系(r=0.9999),平均回收率为99.79%,RSD为1.04%。结论紫外分光光度法准确可靠,可作为倍他米松酊中倍他米松含量的测定方法。Objective To establish the assay method for determining the levels of betamethason. Methods With water bath method to dry out dimethyl sulphoxide and to eliminate its distublance. Ultraviolet spectrophotometric method was used to detect the levels of betamethason. Results There existed satisfactory linear relationship between betamethason level and ultraviolet wavelength（ r =0. 999 9）. Average recovery rate was 99.79%, and RSD was 1.04%. Conclusion The proposed method is accurate and reliable, it can be a feasible assay method to determine the levels of betamethason in betamethason tincture.

关 键 词：倍他米松 紫外分光光度法 含量测定 水浴蒸干 

分 类 号：R927.2[医药卫生—药学] R977.1