非ST段抬高的急性冠状动脉综合征患者心率震荡的临床分析——附21例报告  

Clinical investigation of heart rate turbulance in patients with non-ST segment elevation acute coronary syndrome.

作　　者：杜令[1] 陈华文[1] 王琳[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院心内科,430032

出　　处：《新医学》2006年第9期576-578,共3页Journal of New Medicine

摘　　要：目的研究非ST段抬高的急性冠状动脉综合征(non-STsegmentelevationacutecoronarysyndrome,NSTEACS)患者的心率震荡特点,并评价心率震荡测量指标对预测NSTEACS危险性的价值。方法21例NSTEACS为病例组,选择同期20名体格检查的健康人为对照组,比较两组的震荡起始和震荡斜率,同时分析震荡起始与左心室射血分数(leftventricularejectionfraction,LVEF)、肌钙蛋白I、每5min平均正常窦性心搏间期的标准差(standarddeviationofper-5minaveragesnormalnumberofintervals,SDANN)的相关性。结果病例组震荡起始值显著高于对照组(-0·0139±0·0013、-0·0622±0·0368,P<0·05);两组间震荡斜率值差异无统计学意义。震荡起始值与LVEF和SDANN呈负相关。结论NSTEACS患者的心率震荡指标震荡起始较正常健康组明显增高,且与传统评价NSTEACS的危险性指标LVEF、SDANN有较好的相关性,震荡起始有可能作为预测NSTEACS患者危险性的指标。Objective： To study the phenomenon of heart rate turbulanee in patients with non-ST segment elevation acute coronary syndrome （NSTEACS）. Methods： Turbulance onset （TO） and turbulance slope （TS） were measured in 21 patients with NSTEACS and 20 healthy people as control. Left ventricular ejection fraction （ LVEF）, cardiac troponin I （CTnI） and standard deviation of per-5 min average normal number of intervals （SDANN） were also measured. Results ： TO was significantly higher in patients than that in healthy people （ -0. 0139±0. 0013 and -0.0622±0.0368, P〈0.05 ）. But there was no significant difference in TS between patients and healthy people. TO was negatively correlated with LVEF and SDANN. Conclusion： TO is significantly higher in NSTEACS patients than that in healthy people, and TO is well correlated with some traditional risk factors in NSTEACS patients. TO can be used as a potential risk predictor in NSTEACS patients.

关 键 词：急性冠状动脉综合征 心率震荡 震荡起始 震荡斜率 左心室射血分数 

分 类 号：R541.4[医药卫生—心血管疾病]