中药白芨凝胶经气道介入性治疗增殖型支气管结核的临床评价  

Clinical evaluation of treating bronchial tuberculosis with transluminal hyacinth bletilla gel through air passage

作　　者：孙昕[1] 范勇[1] 杜钟珍[1] 刘钢[1] 梁春宝[1] 韩炳森[1] 

机构地区：[1]天津市海河医院呼吸科,天津300350

出　　处：《中国内镜杂志》2006年第8期832-834,837,共4页China Journal of Endoscopy

摘　　要：目的评价凝胶经气道介入治疗增殖型支气管结核(EBTB)的疗效,筛选理想的凝胶载体。方法应用自行研制的白芨凝胶、羧甲基纤维素钠凝胶经气道介入治疗增殖型EBTB13例、14例,雾化吸入治疗8例,比较3组疗效。结果2个月气管恢复正常各组分别为69.2(%9/13)、64.3(%9/14)、12.5(%1/8),介入治疗与雾化治疗比较差异均有显著性(P<0.05),介入两组之间差异无显著性(P>0.05);6个月时:83.3%(10/12)、84.6(%11/13)、37.5(%3/8),三组比较差异均无显著性(P>0.05)。各期痰菌阴转率白芨组较高,各组比较差异均无显著性。结论应用凝胶剂经气道介入治疗增殖型EBTB具有作用迅速、疗效显著、安全无创及操作简便等特点。白芨凝胶的一些特性,使其较SCMC凝胶更具有临床优势。[Objective] To evaluate the therapeutic effect of transluminal hyacinth bletilla gel to hypertrophic bronchial tuberculosis（EBTB）, so as to select a kind of proper gel carrier. [Methods] 13 patients and 14 patients suffering from EBTB were treated with transluminal hyacinth bletilla gel and carboxylmethyl cellulose gel respectively, which was provided by ourselves, and another 8 cases were treated by inhalation, then therapeutic effect of the three group was evaluated. [Results] Patients with bronchi recovery were 69.2%（9/13）, 64.3%（9/14） and 12.5% （1/8） in the three groups respectively after 2 months treatment, and there were significant differences between transluminal and inhalation group （P 〈0.05）, whereas no difference between the two translumical groups （P 〉0.05）, but there was no significant difference among the three groups after 6 months with recovery rate of 83.3% （10/12）, 84.6%（11/13）, 37.5%（3/8） respectively（P 〉0.05）. The clearing rate of bacillus in sputum was the highest in hyacinth bletilla gel group, but there was no significant difference among the three groups. [Conclusion] Transluminal assay had many characteristics including reacting quickly, effective, safety and operating easily. According to these characteristics, hyacinth bletilla gel is better than SCMC gel in the clinical treatment.

关 键 词：气管-支气管结核 介入治疗学 白芨凝胶 

分 类 号：R523[医药卫生—内科学]