几种辛香中药对辣椒碱巴布剂促透皮吸收作用的研究(英文)  

The Research for the Absorption Function of Fragrant Traditional Chinese Medicine Drug to Capsaicin

作　　者：郝保华[1] 马玲 徐花荣[1] 岳奇峰[1] 

机构地区：[1]西北大学生命科学学院,西安710069 [2]西安现代化学研究所,西安710065

出　　处：《天然产物研究与开发》2006年第4期637-639,共3页Natural Product Research and Development

摘　　要：通过对辛香中药的研究筛选辣椒碱巴布剂的透皮吸收促进剂,提高辣椒碱的透皮扩散速率。采用分别在辣椒碱巴布剂中添加薄荷醇、冰片、桉叶油3种辛香类中药的方法,以月桂氮酮为对照,进行透皮渗透试验。结果表明3种辛香类中药和月桂氮酮对药物的迁移都有一定的促进作用,其中以桉叶油最为突出,其次为冰片、薄荷、氮酮。To observe the enhancement of the diffusion rate of eapsaicin permeating through the skin by screening several complex accelerators for transdennal drug delivery system （TDS） containing capsaicin. Azone, bomeol,ineolic oil,mint was used as the penetration enhancers to study the capsaicin transdermal permeation rate. These four penetration enhancers have a certain action on promoting capsaicin,the result was：ineolic oil is the best one.

关 键 词：巴布剂 透皮吸收 透皮吸收促进剂 辣椒碱 

分 类 号：R285[医药卫生—中药学]