1－（2，6－二甲基苯氧基）－2－（3，4－二甲氧基苯乙氨基）丙烷盐酸盐对兔血小板胞浆游离钙浓度的影响  

EFFECTS OF 1-(2,6-DIMETHYLPHENOXY)-2-(3,4-DIMETHOXY PHENYLETHYLAMINO)PROPANE HYDROCHLORIDE ON CYTOSOLIC FREE CALCIUM CONCENTRATION OF RABBIT PLATELETS

作　　者：夏敬生[1] 罗湘[1] 曾繁典[1] 

机构地区：[1]同济医科大学临床药理研究室

出　　处：《药学学报》1996年第11期872-874,共3页Acta Pharmaceutica Sinica

摘　　要：１－（２，６－二甲基苯氧基）－２－（３，４－二甲氧基苯乙氨基）丙烷盐酸盐对兔血小板胞浆游离钙浓度的影响夏敬生，罗湘，曾繁典（同济医科大学临床药理研究室，武汉４３００３０）１－（２，６－二甲基苯氧基）－２－（３，４－二甲氧基苯乙氨基）丙烷盐酸盐［１－（...The effects of 1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane hydrochloride(DDPH)and verapamil on cytosolic free calcium concentratiOn of rabbitplatelets were investigated.The results showed that the elevation of cytosolic free calciumconcentration([Ca2+]i)of rabbit platelets following ionophore A23187 was significantly inhibited byDDPH and verapamil.The rates of inhibition with DDPH and verapamil were 58 % and 78 %,respectively,with no significant difference between the two groups(P>0.05).

关 键 词：丙烷盐酸盐 DDPH 盐酸非洛普 抗心律失常药 

分 类 号：R972.2[医药卫生—药品]