广谱抗肠道寄生虫药硝唑尼特(nitazoxanide)研究进展  

The progress in investigation of a broad-spectrum intestinal antiparasitic drug——nitazoxanide

作　　者：沈一平[1] 管晓虹[1] 冯振卿[1] 

机构地区：[1]南京医科大学,卫生部抗体技术重点实验室210029

出　　处：《国际医学寄生虫病杂志》2006年第4期221-224,共4页International JOurnal of Medical Parasitic Diseases

摘　　要：硝唑尼特是一种新的广谱抗肠道寄生虫药。它是自苯丙咪唑类药问世30多年来值得注意的一个新发展。它的广谱活性对许多种类的原虫,特别如肠道孢子形成类原虫,以及许多常见的蠕虫,包括绦虫、线虫和吸虫均有特效。进一步的临床和基础研究将有利于使该药更有效地应用。Nitazoxanide（NTX） is a novel broad-spectrum intestinal antiparasitic drug. It is a noteworthy development since the introduction of benzimidazole in more than 30 years. The spemrum of activity of NTZ is effective against a wide range of intestinal protozoa, especially intestinal spore-forming protozoa, and a lot of common helminths, including cestodes, trematodes, nemotodes. Further clinical and basic researches should be encouraged to validate the use of this drag.

关 键 词：硝唑尼特 广谱抗肠道寄生虫药 原虫 蠕虫 绦虫 吸虫 线虫 

分 类 号：R446[医药卫生—诊断学] R574[医药卫生—临床医学]