肾虚肝郁型LUFS卵巢动脉血流动力学特点及罗氏调经种子丸的调节作用  

Hemodynamic Changes of Ovarian Artery in Luteinized Unruptured Follical Syndrome Patients with Kidney Deficiency and Liver Stagnation and Regulatory Effect of Luoshi Tiaojing Zhongzi Pill

作　　者：赵萍[1] 潘莹莹[1] 张玉珍[1] 刘柯兵[1] 

机构地区：[1]广州中医药大学第一附属医院,广州510405

出　　处：《广州中医药大学学报》2006年第5期394-396,共3页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：广东省中医药管理局资助课题(编号:101073)

摘　　要：【目的】分析肾虚肝郁型黄素化未破裂卵泡综合症(LUFS)患者卵巢动脉的血流动力学特点及罗氏调经种子丸的调节作用。【方法】应用阴道彩色多普勒超声检测30例有正常排卵周期的健康妇女(正常组)和20例肾虚肝郁型LUFS患者(LUFS组)治疗前后排卵期和黄体各期排卵侧卵巢动脉的阻力指数(RI)和搏动指数(PI)。【结果】正常妇女卵泡期和黄体各期卵巢动脉RI和PI呈规律性变化:卵泡期的RI和PI较黄体各期均显著性增高,卵巢动脉在卵泡期呈高阻力状态,卵巢动脉RI、PI从黄体早期开始降低,在黄体中期达最小值,到黄体晚期则开始明显回升。肾虚肝郁型LUFS患者治疗前月经各期排卵侧卵巢动脉始终保持高阻力状态,卵泡期和黄体各期RI、PI相接近,即RI、PI从卵泡期到黄体中期均无明显改变,失去原有周期性变化规律。治疗后患者月经各期排卵侧卵巢动脉RI、PI按卵泡期、黄体早期、黄体中期顺序依次呈显著性降低,到黄体晚期又开始回升(黄体各期与治疗前比较,P<0.05或P<0.01),基本恢复了正常妇女排卵侧卵巢动脉RI和PI的规律性变化(各期与正常组比较,均P>0.05)。【结论】罗氏调经种子丸能有效调节LUFS患者卵巢动脉的血流灌注,恢复月经周期正常的变化规律。[Objective] To analyze the hemodynamic changes of ovarian artery in luteinized unruptured follical syndrome （LUFS） patients with kidney deficiency and liver stagnation, and to observe the regulatory effect of Luoshi Tiaojing Zhongz/ Pill （LTZP） on the blood flow of ovarian artery. [Methods] Intraovarian artery resistance index （RI） and pulse index （PI） in 20 LUFS patients with kidney deficiency measured by transvaginal color Doppler sonography during the medication. [ Results] In the healthy volunteers, there existed and liver stagnation and 30 healthy volunteers were ovulatory period and luteal phase before and after periodic changes in intraovarian artery RI and PI： RI and PI increased significantly during follicular phase than those during luteal phase, ovarian arteries were in high resistance during follicular phase, and RI and PI began to decrease in early luteal phase, arrived to the lowest levels in the middle luteal phase and then rose up in the late luteal phase. In LUFS patients with kidney deficiency and liver stagnation before medication, ovarian arteries remained in high resistance during the menstrual cycle, and RI and PI were similar during follicular phase and luteal phase, indicating that there had no periodic changes in intraovarian artery RI and PI. After medication, there occurred periodic changes in intraovarian artery RI and PI of LUFS patients （ P 〉 0.05 as compared with those in the healthy） ： RI and PI decreased in the sequence of follicular phase, early luteal phase and middle luteal phase, and then rose up in the late luteal phase （ P 〈 0.05 or P 〈 0.01 as compared with those in luteal phases before medication）. [ Conclusion] LTZP can regulate the ovarian artery blood flow and recovery the normal periodic changes of menstrual cycle in LUFS patients.

关 键 词：黄素化未破裂卵泡综合症/中药疗法 罗氏调经种子丸/治疗应用 卵巢/药物作用 血流动力学 超声检查 多普勒 彩色 

分 类 号：R271.14[医药卫生—中医妇科学]