铅接触者红细胞嘧啶5′－核苷酸酶活性与其他生物监测指标相关关系研究  

Correlation between erythrocyte pyrimidine 5′-nucleotidase(P5N)and other biological monitoring indices in lead-exposed workers

作　　者：王玉芝[1] 李忠[1] 沈航 刘永珍[2] 吴立文[2] 尹龙赞 王洪飞 田春寅 

机构地区：[1]沈阳市劳动卫生职业病研究所 [2]沈阳市第九人民医院 [3]沈阳市蓄电池厂职防所

出　　处：《中国工业医学杂志》1996年第6期334-335,共2页Chinese Journal of Industrial Medicine

摘　　要：本文在２０名接触铅和２０名非接触铅工人中，进行了红细胞嘧啶５－核苷酸酶（Ｐ５Ｎ）活性，血铅（ＢＰｂ）及尿中δ－氨基乙酰丙酸（δ－ＡＬＡ）测定，并进行相关分析。结果在２０名接触铅工人中红细胞Ｐ５Ｎ活性明显低于对照组并与ＢＰｂ有很好的负相关关系（ｒ＝－０．５１），与尿δ－ＡＬＡ也有负相关关系（ｒ＝０．３１）。In the paper the erythrocyte pyrimidine 5′-nucleotidase(P5N)activity,blood lead(BPb)and urinary δ-aminolevalinic acid(δ-ALA)levels in 20 lead-exposed workers and 20 control workers were studied, and correlative analysis among them were performed too.The results showed that the P5N activity was significanty lower in lead-exposed workers than that of the control group, and was negatively correlated with blood lead(r=-0.51)and urinary δ-ALA(r=-0.31).It was suggested that the P5N activity might be one of the most reliable indicators for lead exposure.

关 键 词：铅 血铅 尿δ-ALA P5N 生物监测指标 指标 

分 类 号：R135.11[医药卫生—劳动卫生]