培朵普利 卡维地洛滴定法治疗扩张型心肌病  

Parindopril and Carvidilol with Dosage Titration Therapy for Dilated Cardiomyopathy

作　　者：王现青[1] 张连仲[1] 牛振民[1] 张嘉莹[1] 高传玉[1] 

机构地区：[1]河南省人民医院心内科,郑州市450003

出　　处：《医药论坛杂志》2006年第15期12-13,共2页Journal of Medical Forum

摘　　要：目的探讨滴定法治疗扩张型心肌病的疗效。方法联合应用洋地黄类、利尿剂、雅施达和络德于56例中重度扩张型心肌病患者,采用剂量滴定法给药,随着治疗时间的延长、疗效的改善,洋地黄类、利尿剂采用逐渐减量,而雅施达和络德采用逐渐加量,直至达到最大耐受量。结果经综合治疗后总有效率91.07%。无洋地黄中毒发生。结论运用剂量滴定法联合治疗扩张型心肌病是简便易行、较少发生不良反应的好方法。Objective To explore the effects of dosage titration therapy for treatment of dilated cardiomyopathic patients. Methods 56 patients with dilated cardiomyopathy were given digoxin,diuretic, parindopril and carvidilol with dosage titration therapy. With the treatment period prolonged, the cardiac function was improved,the digoxin and diuretic dosage minimized, but the dose of parindopril and carvidilol maximized until the patients got maximum tolerable dose. Results 56 patients with combined therapy got good results, the effective rate was 91.07% , no patients occurred digitalis intoxication. Conclusion patients is easy and convinence Using the dosage titration therapy to treat the dilated cardiomyopathic and less adverse effect occurred.

关 键 词：扩张型心肌病 剂量滴定法 左室重塑 

分 类 号：R542.2[医药卫生—心血管疾病]