Study on Double-Strand Break of DNA Irradiated by γ Rays  

作　　者：KONG Fu-quan, ZHAO Kui, SUI Li, CAI Ming-hui, YANG Ming-jian 

出　　处：《Annual Report of China Institute of Atomic Energy》2005年第1期90-91,共2页中国原子能科学研究院年报（英文版）

基　　金：Supported by National Natural Science Foundation of China (10175095,10435020) and President Foundation of China Institute of Atomic Energy

摘　　要：DNA is considered to be the most important bio-macromolecule and target molecule responsible for all biological effects. Many kinds of damage can be induced by radiation, such as base damage, single strand break（SSB）, double strand break（DSB） and crosslink of DNA and protein. DNA double strand breaks（DSBs） are considered to be the most important initial damage of all biological effects induced by high-LET heavy ions radiation. In particular, unrejoined DSBs are responsible for cell death.

关 键 词：电离辐射 DNA损伤 Γ射线 双键断裂 重离子 相对生物学效应 

分 类 号：Q691[生物学—生物物理学]