^(99m)Tc甲氧基异丁基异腈定位显像诊断甲状旁腺功能亢进症  

The diagnostic significanac of ^(99m)Tc MIBI on mage location of hyper parathyroidism

作　　者：刘鸿娥[1] 马步成[1] 崔霞[1] 袁贺匀[1] 李晓鸣[1] 李环[1] 

机构地区：[1]中日友好医院核医学科,北京100029

出　　处：《中日友好医院学报》2006年第4期214-216,共3页Journal of China-Japan Friendship Hospital

摘　　要：目的:评价99mTc甲氧基异丁基异腈(MIBI)双时相显像法对甲状旁腺功能亢进(甲旁亢)的诊断价值。方法:21例临床诊断甲状旁腺功能亢进患者,静注注入99mTcMIBI740MBq(20mCi),分别于10～20min(早期显像)、2h(延迟显像)采集颈部至上胸部的前位平面像。结果:5例原发性甲旁亢患者均表现为孤立的放射性浓聚灶;16例继发性甲旁亢中,2例显示为单个放射性浓聚灶,10例显示为2个放射性浓聚灶,2例显示为3个放射性浓聚灶;另有2例显示有异位甲状旁腺病灶。10例经手术证实甲旁亢患者中,术前99mTcMIBI甲状旁腺显像和超声诊断检查,对原发性甲旁亢患者定位诊断阳性率均为100%,对继发性甲旁亢患者定位诊断阳性率分别为55%和70%。结论:99mTcMIBI双时相法显像在甲旁亢患者中有较高的定位诊断价值。Objective：To evaluate the diagnostic value of ^99mTc MIBI double phase parathyroid scintigraphy in the hyperparathyroidism patients.Methods：^99mTc MIBI double phase parathyroid scintigraphy was performed in 21 patients.Planar imaging of the neck and thorax is recorded starting 10～20 min and then 2h after the intravenous injection of ^99mTc MIBI 740MBq（20mCi）.Results：Five patients with primary hyperparathyroidism had solitary lesion; and 16 patients with secondary hyperparathyroidism：pmong them two patients had solitary lesion,ten patients had two lesions,two patients had three lesions and the other two patients had ectopic parathyroid glands.Preoperative uhrasonography and ^99mTc MIBI imaging were 100% conforming to the location in the primary hyperparathyroidism,but 70% and 55% respectively in the secondary hyperparathyroidism, verified by intraoperative findings in ten patients.Conelusion：^99mTc MIBI double phase parathyroid scintigraphy is an useful imaging method for the localization diagnosis of the hyperparathyroidism.

关 键 词：甲状旁腺功能亢进症 ^99mTC甲氧基异丁基异腈 

分 类 号：R582.1[医药卫生—内分泌]