黄芪对腹膜透析病人腹膜超微结构的影响  

Effect of Astragalus Injection on the Ultrastructure of Human Peritoneum During Peritoneal Dialysis

作　　者：徐家云[1] 王俊霞[1] 孟晓青[1] 卢丹萍[1] 杨芳[1] 张春荣[1] 张国胜[1] 

机构地区：[1]河南科技大学第一附属医院,河南洛阳471003

出　　处：《陕西中医学院学报》2006年第5期51-53,共3页Journal of Shaanxi College of Traditional Chinese Medicine

基　　金：河南省自然科学基金(0411041200)

摘　　要：目的探讨黄芪对腹膜透析(腹透)病人腹膜,间皮层超微结构的影响及其意义。方法采用光镜、扫描电镜和透射电镜对4组患者的腹膜活检标本进行形态学观察。结果尿毒症非腹透患者腹膜超微结构与正常对照者相似,而应用黄芪腹透患者的腹膜超微结构的退行变化较非应用黄芪的腹透患者为轻。结论长期腹透可引起腹膜功能衰竭,而腹膜形态结构的改变是最重要原因之一,应用黄芪进行干预对腹膜结构有一定的保护作用。To study the effect of astragalus injection （ 黄芪注射液, AI ） on the ultrastructure of human peritoneum during peritoneal dialysis. Methods ： Peritoneal morphology of four growps of padients, Peritoneal biopsies was studied by light microscopy, scanning electron microscopy and tramsmission electron microsco- py. Results： The peritoneal morphology of uremic non - peritoneal dialysis was similar to that of normal subject. Peritoneal ultrastructure changes was slighter the group that use AI compared with the group usnt AI. Conclusion： PD can modify peritoneal morphology and structure. The morphological change is progressive and might be one of the important causes of peritoneal failure. Peritoneal membrane was protected that use AI.

关 键 词：腹膜透析 形态学 超微结构 腹膜活检 

分 类 号：R282.71[医药卫生—中药学]