双生子儿童体格发育指标遗传度分析  

Analysis on heritabilities of physical growth items in child twins

作　　者：李玉玲[1] 季成叶[1] 陆舜华[2] 刘海萍[2] 徐轶群[1] 陈天娇[1] 

机构地区：[1]北京大学儿童青少年卫生研究所,北京100083 [2]内蒙古师范大学生命科学与技术学院

出　　处：《中国公共卫生》2006年第9期1040-1041,共2页Chinese Journal of Public Health

基　　金：国家自然科学基金(30371223);2003年度教育部博士点基金(20030001043)

摘　　要：目的分析儿童体格发育指标的遗传度，探讨遗传与环境因素对各发育特征的影响程度。方法测量218对6～13岁同性别双生子的9项体格发育指标，分性别对年龄进行校正后，用组内相关系数法计算各指标遗传度。结果多数指标的遗传度在60％以上，且在一定程度上存在性别差异。结论遗传因素对儿童发育起主要作用，性别对体重、头长和头宽遗传度的影响最为明显。Objective To analyze the heritabilities of physical growth items anditsrelated factors. Methods 9 development items of 218 twin pairs aged 6 to 13 were investigated. The heritabilities were estimatded using intraclass correlation coefficient from the adjusted data for age. Results Most of the estimated heritabilities of these items were above 60 %, and with sex difference to some extent. Conclusion Child development is mainly determined by the genetic factors. The effect of gender on heritabilities is more obvious for weight, head length and head breadth than other items.

关 键 词：双生子 儿童发育 遗传度 

分 类 号：R179[医药卫生—妇幼卫生保健]