2-氰基-3-取代吡啶甲胺基-3-取代丙烯酸乙氧乙酯的合成和除草活性研究  

Synthesis and Herbicidal Activity of Ethoxyethyl 2-Cyano-3-(substituted)pyridinemethylamino-3-(substituted)acrylates

作　　者：刘玉秀[1] 李姮[1] 赵奇奇[1] 汪清民[1] 黄润秋[1] 

机构地区：[1]南开大学元素有机化学研究所元素有机化学国家重点实验室,天津300071

出　　处：《有机化学》2006年第9期1232-1238,共7页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.20272030);全国优秀博士学位论文作者专项资金(No.200255)资助项目.

摘　　要：一系列2-氰基-3-取代吡啶甲胺基丙烯酸酯被合成作为光合作用光系统II电子传递抑制剂.生测发现一些目标化合物表现出很好的除草活性,如(Z)-2-氰基-3-异丙基-3-(2-烷氧基取代的吡啶-3-基)甲胺基丙烯酸乙氧乙酯.生测结果表明在吡啶环的2位合适的取代基和丙烯酸酯的3位取代基的体积对除草活性至关重要.A series of 2-cyano-3-（substituted）pyridinemethylaminoacrylates were synthesized as herbicidal inhibitors of photosystem Ⅱ （PSⅡ） electron transport and their herbicidal activities were evaluated. Some of them exhibited excellent herbicidal activities, especially （Z）-ethoxyethyl 2-cyano-3-isopropyl-3-（2- alkoxypyridin-3-yl）methaneaminoacrylate. These results indicated that a suitable substituent at the 2-position of pyridine ring and a well-fit group at the 3-position of acrylate were both essential for high herbicidal activity.

关 键 词：氰基丙烯酸酯 光系统Ⅱ 电子传递抑制剂 除草活性 吡啶环 

分 类 号：TQ450.2[化学工程—农药化工]