离子液体/水混合溶剂促进芳醛与罗丹宁的缩合反应  

Ionic Liquid/H_2O System Promoted Condensation of Aromatic Aldehydes and Rhodanine

作　　者：练习中[1] 李毅群[1] 周美云[1] 

机构地区：[1]暨南大学化学系,广州510632

出　　处：《有机化学》2006年第9期1272-1274,共3页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.20272018);广东省自然科学基金(Nos.04010458;021166)资助项目.

摘　　要：在室温条件下,离子液体1-正丁基-3-甲基咪唑四氟硼酸盐([bmim]BF4)与水组成的混合溶剂能有效催化一系列芳醛与罗丹宁反应,以80%～93%的产率生成相应的5-芳亚甲基-2,4-噻唑二酮.离子液体[bmim]BF4催化活性高,反应在10～120min内完成.实验结果表明该法反应条件温和、产率高、反应时间短、后处理简单、离子液体可重复使用.The mixed solvent of ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate and water has efficiently promoted the synthesis of a variety of 5-arylmethylidene-4-oxo-2-thiothiazolidines from the corresponding aromatic aldehydes and rhodanine at room temperature in 80%-93% yields within 10 to 120 min. The present protocol offered several advantages including mild conditions, high yields, short reaction time, and simple work-up procedure. Moreover, the ionic liquid was reusable.

关 键 词：离子液体 芳醛 罗丹宁 5-芳亚甲基-2 4-噻唑二酮 

分 类 号：O621.25[理学—有机化学]