乙型病毒性肝炎肝组织不同炎症分级与CD8^+淋巴细胞数量的关系  

Vary of CD8^+ Lymphocyte in Liver Tissue with Virious Inflammation Grades of Hepatitis B and its Clinical Implication

作　　者：陆忠华[1] 裴浩[1] 居朝霞[1] 丁虹[1] 

机构地区：[1]无锡市传染病医院肝脏病理研究室,214007

出　　处：《国际免疫学杂志》2006年第5期339-340,F0003,共3页International Journal of Immunology

摘　　要：目的探讨CD8+淋巴细胞与乙型肝炎病人肝组织炎症分级的关系和意义。方法应用免疫组化技术检测不同炎症分级的肝组织中CD8+淋巴细胞的数量的变化。结果G0肝组织中CD8+数量减少,随着炎症分级的增强,CD8+淋巴细胞数量增加。G4最为明显,有明显统计学意义。结论CD8+淋巴细胞数量的变化与肝组织炎症分级有明显相关性。Objective To investigate the vary and clinical meaning of CD8^＋ lymphocyte in liver tissue virious inflammation grades of hepatitis B. Methods The vary of CD8^＋ lymphocyte was evaluated by immunohisto-chemistry in liver tissue virious inflammation grade of hepatitis B. Results In liver tissue of inflammuation Go, the CD8^＋ lymphocytes were showed low Level. The higher inflammation grades in liver tissue, the more quantity of CD8 ^＋ lymphocyte. The vary of CD8^＋ lymphocyte in liver tissue inflammation G4 was the most obivious, they had apparent statistical significance. Conclusion The vary of CD8 ^＋ lymphocyte and liver tissue inflammation grades had apparent relativity.

关 键 词：肝组织炎症分级 CD8^+淋巴细胞 免疫组织化学染色 

分 类 号：R512.62[医药卫生—内科学]