心肌存活性的检查和早期干预治疗进展性左室收缩功能不全的效果  

Myocardial viability testing and the effect of early intervention in patients with advanced left ventricular systolic dysfunction

作　　者：秦春常 

出　　处：《中国分子心脏病学杂志》2006年第2期114-114,共1页Molecular Cardiology of China

摘　　要：背景：评价在严重左室收缩性心衰的患者血管重建和其他治疗的临床价值还不是很清楚。用氟脱氧葡萄糖（FDG）正电子（PET）成像来评价患者心肌缺血和存活性可以鉴别接受血管重建的病人可能提高生存率。我们实行倾向分析决定患者通过血管重建是否获得生存好处。方法和结果：我们分析1997到2000年在Cleveland医学中心765病人（年龄64±11岁，80％男性），合并进展性左室收缩功能不全（射血分数≤35％）并且没有明显的瓣膜疾病，接受PET／FDG研究。早期干预治疗定义为心脏干预（手术或经皮介入）在头6个月进行PET／FDG研究。BACKGROUND： The clinical value of revascularization and other procedures in patients with severe systolic heart failure is unclear. It has been suggested that assessing ischemia and viability by positron emission tomography （PET） with fluorodeoxyglucose （FDG） imaging may identify patients for whom revascularization may lead to improved survival. We performed a propensity analysis to determine whether there might be a survival advantage from revascularization. METHODS AND RESULTS ： We analyzed the survival of 765 consecutive patients （ age 64 ＋ / -11 years, 80% men） with advanced left ventricular systolic dysfunction （ejection fraction 〈 or = 35% ） and without significant valvular heart disease who underwent PET/FDG study at the Cleveland Clinic between 1997 and 2002.

关 键 词：左室收缩功能不全 早期干预治疗 心肌存活性 进展性 检查 血管重建 氟脱氧葡萄糖 收缩性心衰 

分 类 号：R541.6[医药卫生—心血管疾病]