脂蛋白脂酶(LPL)HindⅢ基因多态性与血脂和冠心病及运动关系的研究进展  

The Research Development on the Relationships of LPL HindⅢ Gene Polymorphisms between Serum Lipids,Coronary Heart Disease and Exercise

作　　者：刘艳环[1] 马国梁 赵斐[3] 张勇[3] 

机构地区：[1]山东理工大学体育学院,淄博255049 [2]山东省沂水县沂水镇第三中学,沂水276400 [3]天津体育学院运动医学研究所,天津300381

出　　处：《天津体育学院学报》2006年第5期412-415,共4页Journal of Tianjin University of Sport

摘　　要：脂蛋白脂酶(LPL)基因多态性与血脂及冠心病关系密切,因此目前对脂蛋白脂酶基因多态性研究相对较多,但主要集中在HindⅢ酶切位点。脂蛋白脂酶基因HindⅢ酶切位点多态性可产生3种基因型H+H+、H+H-、H-H-,不同基因型与血脂成分及冠心病关系密切程度各异,另外,运动对不同基因型个体血脂影响不同。就脂蛋白脂酶HindⅢ酶切位点多态性与血脂和冠心病及运动关系作一综述。There was a closed relationship among lipoprotein lipase gene polymorphisms, serum lipids and coronary heart disease （CAD）, so more and more researches on it occurred, but most investigations were concentrated on lipoprotein lipase Hindm gene polymorphisms, which has three genotypes, H^＋H^＋, H^＋H^- and H^-H^-. Different genotypes have different effects on serum lipids and CAD. Exercise on serum lipids produced discrepant influences in diverse genotypes. In this article, the authors reviewed the relationships of LPL Hindm gene polymorphism between serum lipids, coronary heart disease and exercise.

关 键 词：基因多态性 血脂 冠心病 运动 

分 类 号：G852.19[文化科学—民族体育]