喹诺酮类抗茵药的研究进展  

Progress in research of quinolone antibacterials

作　　者：张宇[1] 

机构地区：[1]北京双鹤药业股份有限公司,北京100102

出　　处：《中国新药杂志》2006年第16期1344-1350,1356,共8页Chinese Journal of New Drugs

摘　　要：综述了近年喹诺酮类抗菌药的抗菌活性和临床应用进展,包括近年上市的第四代喹诺酮类抗菌药莫西沙星、加替沙星、吉米沙星和巴洛沙星,与结构经进一步深入修饰的喹诺酮类抗菌药如帕珠沙星和鲁利沙星,还概述了正在研发中的新药。The progress in research of quinolone antibacterials in recent years were reviewed, which include 4-th generation quinolones moxifloxacin, gatifloxacin, gemifloxacin, balofloxacin and quino- lones with deeper modified structure. New agents under development were also summarized.

关 键 词：喹诺酮类抗菌药 第四代喹诺酮 莫西沙星 加替沙星 吉米沙星 巴洛沙星 

分 类 号：R978.1[医药卫生—药品]