甘草酸及其衍生物的研究进展  

Research Progress on Glycyrrhizic Acid and Its Derivatives

作　　者：索田栋[1] 张军良[1] 郭燕文[1] 叶彦春[1] 来庚[1] 

机构地区：[1]北京理工大学理学院化学系,北京100081

出　　处：《精细与专用化学品》2006年第17期13-16,28,共5页Fine and Specialty Chemicals

摘　　要：根据糖给体的数量将甘草酸衍生物进行了分类,其中包括单糖-甘草次酸、二糖-甘草次酸和多糖-甘草次酸衍生物,并分别对其药理活性和合成方法进行了综述。研究发现,由于氨基酸类的衍生物有更强的药理活性,在近几年得到了很大的发展。Depending on the number of aglycones, the classification of glycyrrhizic acid derivatives has been carried out, including monosaccaride-glycyrrhetic acid, disaccharide-glycyrrhetic acid and polysaccarides derivatives. Their pharmacological activities and synthetic methods are summarized. The research results show that amino acid based derivatives with strong pharmacological activity have been developed rapidly in recent years.

关 键 词：甘草酸 甘草次酸 抗SARS 抗溃疡 抗肿瘤 

分 类 号：R284[医药卫生—中药学]