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作 者:王钝[1] 金文淑[2] 秦恩伟[1] 王硕冰[1] 李鹏[1]
机构地区:[1]沈阳药科大学制药工程学院,辽宁沈阳110016 [2]通化万通药业有限公司,吉林通化134001
出 处:《中国医药工业杂志》2006年第9期584-585,共2页Chinese Journal of Pharmaceuticals
摘 要:Indocyanine green, a diagnostic aid was synthesized from 2,3,3-trimethyl-4,5-benzindole by 4 steps of reactions with an overall yield of 63.7%. As an improvement, sodium acetate was used in the salt formation instead of sodium iodide.Indocyanine green, a diagnostic aid was synthesized from 2,3,3-trimethyl-4,5-benzindole by 4 steps of reactions with an overall yield of 63.7 %. As an improvement, sodium acetate was used in the salt formation instead of sodium iodide.
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