新生儿高胆红素血症心肌肌钙蛋白T的变化  

The variety of cardial troponin T in neonates with hyperbilimbinemia

作　　者：常彩红[1] 牛德亮[2] 

机构地区：[1]郑州大学第三附属医院检验科,450052 [2]河南中医学院第一附属医院检验科

出　　处：《中国妇幼保健》2006年第17期2367-2368,共2页Maternal and Child Health Care of China

摘　　要：目的:探讨新生儿高胆红素血症时心肌肌钙蛋白T(cTnT)的变化及其临床意义。方法:采用化学免疫系统和全自动生化分析仪,对38例高胆红素血症患儿血清cTnT及IBIL进行检测,同时选20例生理性黄疸新生儿作为对照。结果:各组新生儿血清中cTnT水平:重度高胆红素血症组显著高于轻度组(P<0·01)和对照组(P<0·01),轻度组与对照组无显著性差异(P>0·05)。结论:新生儿高胆红素血症可以引起心肌的损害,血清cTnT水平升高程度与IBIL成正相关。cTnT的检测可以为临床治疗提供实验依据。Objective： To detect the variety and the clinical value of cardial, troponin T in neonates with hyperbilirubinemia. Methods： The levels of cTnT and IBIL were measured by full -automatic chemo -immune system and biochemistry system in 38 neonates with hyperbilirubinemia and 20 physio - bilirubinemia nenates as control. Results： The levels of eTnT in serum： increased obviously in severe hyperbilirubinemia group than those of in mild hyperbilimbinemia （P 〈0. O1 ） group and control （P 〈0. O1 ）, there was no significant difference between mild hyperbilirubinemia and control （P 〉0. 05） . Conclusion： The level of cTnT increase greatly as the result of hyperbilirubinemia - induced myocardial damage. The concentrations of serum cTnT and IBIL have notable positive correlation. Monitoring the level of cTnT in serum might provide an index for clinic.

关 键 词：新生儿 高胆红素血症 肌钙蛋白T 心肌损伤 

分 类 号：R722.17[医药卫生—儿科]