氟哌啶醇对多发性抽动症病儿甲状腺功能的影响  

EFFECTS OF HALOPERIDOL ON FUNCTION OF THYROID IN CHILDREN WITH TOURETTE SYNDROME

作　　者：魏鹏[1] 臧东莲[2] 岳旺[2] 

机构地区：[1]青岛市医疗保险管理中心,山东青岛266071 [2]青岛大学医学院药理学教研室

出　　处：《齐鲁医学杂志》2006年第6期515-516,共2页Medical Journal of Qilu

摘　　要：目的探讨氟哌啶醇对多发性抽动症(TS)病儿甲状腺功能的影响。方法将56例TS病儿随机分为用药组35例和对照组21例,采用放射免疫分析法(RIA)进行血清TSH、FT3、FT4水平测定。结果氟哌啶醇对TS病儿TSH、FT3、FT4水平无明显影响(P>0.05),用药时间长者TSH、FT4浓度较高,但也无显著性差异(P>0.05)。结论氟哌啶醇对多发性抽动症病儿甲状腺功能无明显影响。Objective To evaluate the effects of Haloperidol on the function of thyroid in children with Tourette syndrome （TS）. Methods Fifty-six children with TS were randomly divided into two groups： Haloperidol-treated group （n=35） and control group （n= 21）, and their serum concentrations of TSH, FT3 and FT4 were measured by RIA technique. Results No obvious effect of Haloperidol on TSH, FT3 and FT4 was noted （n=35） as compared with that of control group （n= 21）（ P〉 0. 05）. Though the values of TSH and FT4 were higher in those treated longer, the difference was not statistically significant （P〉 0.05）. Conclusion Haloperidol may have no significant influence on the function of thyroid in children with Tourette syndrome.

关 键 词：抽搐性运动障碍 氟哌啶醇 甲状腺激素类 

分 类 号：R971[医药卫生—药品]