480株铜绿假单胞菌耐药性分析  

Drug resistance of 480 strains of Pseudomonas aeruginosa

作　　者：李玉强[1] 

机构地区：[1]河南省平顶山市第一人民医院,平顶山467000

出　　处：《临床医学》2006年第9期76-77,共2页Clinical Medicine

摘　　要：目的了解我院铜绿假单胞菌的耐药现状,为临床用药提供依据。方法将我院分离的铜绿假单胞菌的药敏试验结果,应用WHONET 5.3软件进行统计学分析。结果铜绿假单胞菌对抗菌药物的敏感性逐年下降,三代头孢和喹诺酮类药物下降明显。亚胺培南对铜绿假单胞菌仍保持着98.2%的敏感率,多粘菌素B对铜绿假单胞菌也保持着95.0%的敏感率。结论铜绿假单胞菌耐药严重,医院应加强对铜绿假单胞菌的监测,临床要依据药敏试验结果合理用药。Objective To investigate the drug resistance status of Pseudomonas aeruginosa（PAE）, and to provide reference for clinical treatment in our hospital. Methods The drug susceptibility was tested by Kirby - Bauer method. The data of drug susceptibility tested was analyzed by WHONET 5.3, Results The drug susceptibility of PAE to most antibiotics was a decreasing trend during the past 7 years. The drug susceptibility of the third generation cephalosporins and quinolones was lower. The highest susceptibility to PAE was imipenem（98.2% ） and polymyxin B（95.0% ）. Conclusion The drug resistance of PAE is serious. Supervision of drug resistance of PAE should be strengthened in hospital, lt~ very important to select antibiotics correctly according to the results of susceptibility test in clinic.

关 键 词：铜绿假单胞菌 抗菌药物 耐药性 

分 类 号：R446.5[医药卫生—诊断学]