丙泊酚伍用芬太尼在未经阴道分娩无痛人流的临床应用  

Application of propofol and fentanyl in induced abortion of pregnant women without the history of vaginal delivery

作　　者：吴忠德[1] 陈利维[1] 郑治国[1] 向奎[1] 

机构地区：[1]宣汉县人民医院麻醉科,四川宣汉636150

出　　处：《西部医学》2006年第5期571-572,共2页Medical Journal of West China

摘　　要：目的 研究丙泊酚（异丙酚）联合应用不同剂量的芬太尼在未经阴道分娩病人人工流产手术的麻醉的最佳用量。方法ASAAI～Ⅱ级未经阴道分娩并需要进行人工流产患者90例，随机分为3组，A组使用芬太尼1．0μg／kg，B组使用芬太尼1．5μg／kg，C组使用2．0μg／kg。观察3组患者苏醒时间、呼吸抑制、丙泊酚的总用量、病人身体运动情况，术中病人体动发生等情况。结果　呼吸抑制3组相似（X^2=2．520，P=0．248）：丙泊酚的用量A组高于B、C两组（P＜0．01）；手术中肢动A组高于B、C两组（（X^2=48．445，P=0．000）。结论 丙泊酚联合1．5μg／kg芬太尼在未经阴道分娩病人的人工流产中的麻醉既能增强麻醉镇痛效果，又能减少异丙酚的总用量，呼吸抑制不明显，是一种较安全有效的配伍方法。Objective To explore the anesthetic effect of different dose of propofol and fentanyl on induced abortion of pregnant women who have not the history of vaginal delivery. Methods Ninety cases who were under the necessity of induced abortion were randomly divided into three groups： Group A was administrated fentanyl 1μg/kg; Group B, fentanyl 1.5μg/kg; and Group C, fentanyl 2μg/kg. The time to awake, the total dosage of propofol and the conditions of respiration depression were recorded. Results The magnitude of respiration depression was similar among three groups （X^2= 2. 520, P=0. 248）. The awaking time, propofol dosage, and body movement during operation were less in Groups B and C than Group A （P〈0.01） . Conclusion It is advisable to use propofol combined with fentanyl of 1.5μg/kg for anesthesia of induced abortion in women without the history of vaginal delivery because it can enhance analgesic efficiency, reduce propofol dosage, and meanwhile avoid the drawback of noticeable respiration depression.

关 键 词：丙泊酚 芬太尼 人工流产 

分 类 号：R719.3[医药卫生—妇产科学] R614.24[医药卫生—临床医学]