从形态学角度探讨硒与大骨节病的关系  

A Morphological Study on the Relation Between Selenium and Kaschin-Beck Disease

作　　者：张桂琴[1] 刘锦先 李连群[1] 李春芳 石玉霞[1] 李佳安 冯杰[1] 

机构地区：[1]中国地方病防治研究中心大骨节病研究所

出　　处：《地方病通报》1990年第3期7-10,共4页Endemic Diseases Bulletin

摘　　要：本文搜集具有六指(趾)骨畸形的儿童6例,其中3例确诊为大骨节病。我们采用X线拍片、病理和超微结构的形态学手段,对其进行硒与大骨节病关系的探讨。结果表明硒对软骨坏死未显示出明显的修复作用,低硒不是大骨节病的唯一致病因素;硒可以改善软骨细胞膜性结构及增强膜性结构的功能;拇指外畸形的多指骨变化,不能代表其他手指骨的病变。The relation between selenium and Kaschin-Beck disease in 6 children with polydactylia ( 3 of them with Kaschin-Beck disease) were morphologically studied with X-ray, pathohistologcal and ultrastructural techniques. Results showed that there was no significantly repairable effect of selenium on chondronecrosis of the Kaschin-Beck disease and, deficience of selenium was not the only pathogenic factor of Kaschin-Beck disease. The membrane structure was improved and its function increased by administration of selenium; the changes in polydactylia on the lateral of thumb could not represent the changes in the other fingers.

关 键 词：硒 大骨节病 形态学 

分 类 号：R684.102[医药卫生—骨科学]