胰岛素泵在2型糖尿病并肺部感染的应用效果观察  

Effect of insulin pump in treatment of type two diabetic patients with pulmonary infections

作　　者：赵卫民[1] 邹秀兰[1] 王迎难[2] 杨建明[1] 刘燕群[1] 余萍[1] 杜松涛[2] 

机构地区：[1]湖北省宜昌市第一人民医院内分泌科,443000 [2]湖北省宜昌市第一人民医院呼吸科,443000

出　　处：《中国医师进修杂志》2006年第9期17-19,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的观察应用胰岛素泵进行连续皮下胰岛素输注(CSII)治疗2型糖尿病并肺部感染患者强化血糖控制的疗效。方法将住院的2型糖尿病并肺部感染患者83例随机分为皮下胰岛素泵治疗组(CSII组,42例)和多次皮下注射治疗组(MSII组,41例),观察血糖、血糖下降至正常的时间、肺部感染控制时间、费用及低血糖发生率。结果两组患者的血糖治疗后均明显下降,达目标血糖值的时间、肺部感染控制时间、胰岛素用量、低血糖发生率CSII组较MSII组明显减少(P<0.05);CSII组治疗后糖化血红蛋白、总胆固醇、C-反应蛋白明显降低,而空腹C肽、高密度脂蛋白-胆固醇明显升高(P<0.05)。而MSII组治疗前后上述指标的差异无统计学意义(P>0.05)。结论CSII能更好地控制血糖,纠正代谢紊乱,减少费用和住院天数,并能减少低血糖发生,是较为理想的方法。Objective To study the effect of continuous subcutaneous insulin injection （CSⅡ） in treatment of type two diabetic patients with pulmonary infections. Methods From January 2001 to December 2005,83 type two diabetic patients with pulmonary infections were randomized to group CSⅡ （42 cases） and group MSⅡ （41 cases）. The period of normalization of the blood glucose and cure of the pulmonary infections, cost and morbidity of low blood glucose were observed. Results Blood glucose of all patients in two groups reduced significantly. Significant difference was observed in the period of cure of the pulmonary infections, usage amount of insuhn and morbidity of low blood glucose. In group CSⅡ HbA,c, CRP and CHOL reduced significantly. Fasting CRP and high density hpoprotein-C （HDL-C） were remarkably increased. Conclusions Consecutive subcutaneous insulin pump injection is able to control the blood glucose better, to correct metabolic disorder, reduce the cost and hospital day and decrease the morbidity of low blood glucose. CSⅡ is a better of method.

关 键 词：糖尿病 胰岛素泵 连续皮下注射 多次皮下注射 

分 类 号：R587.1[医药卫生—内分泌] R563.1[医药卫生—内科学]