门控心肌灌注显像对冠状动脉支架术前后左室功能的评价  

Evaluation of gated myocardial perfusion imaging for detecting left ventricular function before and after coronary artery stenting

作　　者：冯建林[1] 李殿富[1] 程旭[1] 李建华[1] 徐兆强[1] 

机构地区：[1]南京医科大学第一附属医院核医学科,江苏南京210029

出　　处：《中国临床医学影像杂志》2006年第9期496-498,共3页Journal of China Clinic Medical Imaging

基　　金：江苏省卫生厅2005年度医学科技发展基金资助(编号H200509)

摘　　要：目的:比较99mTc-MIBI门控心肌灌注显像(G-MPI)测定冠脉支架术前后左心功能相关指标的变化,对手术疗效进行评价。方法:27例患者,术前及术后1～6个月行静息G-MPI测定左室舒张末期容量(EDV)、收缩末期容量(ESV)、左室射血分数(LVEF)并对室壁运动评分。根据术前LVEF分为2组:伴左室功能不全(LVEF≤45%)为Ⅰ组(12例),其余为Ⅱ组(15例)。结果:①Ⅰ组术后EDV、ESV比术前明显减少(P<0.01),LVEF增加(P<0.05);Ⅱ组上述指标手术前后无明显变化(P>0.05)。②术前室壁运动轻中度下降的节段术后82.3%有改善;严重下降29.3%有改善;无运动术后仅15.7%有改善。结论:静息G-MPI在冠脉支架术前及术后随访有重要的临床价值。Objective： To compare the changes of global and regional left ventricular function parameter before and after coronary artery stenting by using ^99mTc-MIBI gated myocardial perfusion imaging（G-MPI） and to evaluate coronary artery stenting effect. Methods： The values of end-diastolic volume（EDV）, end-systolic volume（ESV）, left ventricular ejection fraction （LVEF） and regional wall motion were assessed by rest G-MPI before and 1 to 6 months after coronary artery stenting in 27 patients. All patients were divided into two groups： Group Ⅰ （12 cases） involved patients with left ventricular dysfunction （LVEF≤45%）; the rest were included in group Ⅱ （15 cases）. Results： ① After coronary artery stenting, the values of EDV and ESV were decreased markedly（P〈0.01）, LVEF was increased（P〈0.05） compared with preoperation in group Ⅰ. On the contrary, there were no significant changes of these indexes（P〉0.05） in group Ⅱ. ② There were 93（82.3%） segments improved postoperatively in mild and moderate hypokinesia, 12（29.3%） segments improved in severe hypokinesia, and 3（15.7%） in akinesia. Conclusion： G-MPI is an excellent tool to evaluate the effect of stent implantation, and suitable for long term follow-up.

关 键 词：心室功能 左 支架 门控血池显像 

分 类 号：R331.31[医药卫生—人体生理学] R817.4[医药卫生—基础医学]