大脑半球切除术后双侧脑干听觉诱发电位的研究  

Along┐termstudyofbilateralbrainstemauditoryevokedpotentialsintwentypatientsaftersurgicalhemispherectomy

作　　者：徐宇伦[1,2,3,4] 刘淑玲[1,2,3,4] 刘海一 陈炳桓[1,2,3,4] 谭郁玲 潘映辐[1,2,3,4] 万选才 

机构地区：[1]首都医科大学附属北京天坛医院神经外科 [2]北京市神经外科研究所解放军总医院计算机室 [3]首都医科大学附属友谊医院神经内科 [4]中国协和医科大学基础医学院

出　　处：《中华神经科杂志》1996年第6期336-339,共4页Chinese Journal of Neurology

摘　　要：为了探讨人类脑干听觉诱发电位（ＢＡＥＰｓ）中Ⅲ波及其以后各波的确切神经发生源，对２０例大脑半球切除术后远期继发半侧脑干萎缩的病例进行了双侧ＢＡＥＰｓ和脑干截面积的研究。结果发现，萎缩侧脑干ＢＡＥＰｓ中的Ⅲ波和Ⅴ波潜伏期缩短。此外，萎缩对侧脑干呈代偿性增粗的同时，Ⅴ波波峰绝对潜伏期延长。结果提示：Ⅲ、Ⅴ波的神经发生源位于刺激的同侧。Thepurposeofthestudywastoprobeintothetrueneuralgeneratorsofthebrain-stemaudiotoryevokedpotentialsinhumansafterhemispherectomy,especialywithregardtopeaktheⅢandⅤwaves.Twentypatientswhohadundergonecerebralhemispherectomybetween1985and1992forthealeviationofintractableepilepsywereelectrophysiologicalystudied.Bilateralbrainstemauditoryevokedpotentials(BAEPs)wereaveragedandmappedoutoverthescalp.Asthelongperiodsafterhemispherectomyentailedmassiveretrogradedegenerationofthesemibrainstemontheoperatedside,itwasfoundthatthelatencyofpeakⅢwasshortenontheoperatedside(P<0.05)andthelatencyofpeakⅤwasdelayedonthecontralateralside(P=0.001).TheresultsofthisstudyindicatedthattheneuralgeneratorsofthepeakⅢandⅤshouldbelocatedinipsolateralclickstimulationandpeakⅢaswelaspeakⅤinhumansmayhavecontributionsfromtheipsolateralcerebralcortex.Besides,itwasconsideredthattheneuralgeneratorsmightberelatedtothevolumeconductor.

关 键 词：脑外科手术 大脑半球切除术 脑干听觉 诱发电位 

分 类 号：R651.11[医药卫生—外科学]