鼓室副神经节瘤的诊断与治疗  

Diagnosis and treatment of tympanic paraganglioma

作　　者：王超[1] 金德均[1] 赵金花[1] 李秋影[1] 冯佳鹏[1] 

机构地区：[1]哈尔滨医科大学附属二院,150086

出　　处：《现代生物医学进展》2006年第9期57-58,共2页Progress in Modern Biomedicine

摘　　要：目的：探讨鼓室副神经节瘤的临床和病理特征。方法：复习临床病历资料,采用HE和免疫组化方法研究鼓室副神经节瘤的病理特征。结果：肿瘤实质由上皮样主细胞和短梭形支持细胞组成。主细胞中CgA、NSE和Syn呈阳性表达,支持细胞中S -100蛋白阳性表达。病理诊断为鼓室副神经节瘤,随访2年未见复发征象。结论：鼓室副神经节瘤十分罕见,临床和病理诊断困难,常需借助免疫组化协助诊断。治疗以手术切除为主。Objective： To explore the clinical and pathological characteristics of tympanic araganglioma（TA）. Methods： The clinical data of the patient with TA were reviewed, The tumor was studied by HE and immunohistochemistric stains, Results： The parenchyma of tumor was composed of epithelioid cells（neoplastic chief cells）and spindle sustentaeular cells, In the neoplastic chief cells, CgA, NSE and Syn were positive, In the sustentacular ceils, S- 100 protein was positive. Pathological diagnosis was primary paraganglioma, During two years＇ follow- up, the patient was doing well without signs of tumor recurrence, Conclusion： Tympanic paraganglioma is an extremely rare tumor. It is very difficult in the clinical and pathological diagnoses, which must depend on immunohistochemistrie stains. Surgical excision is mainly performed when treating.

关 键 词：副神经节瘤 临床 病理 免疫组化 

分 类 号：R764.29[医药卫生—耳鼻咽喉科]