强心冲剂治疗慢性充血性心力衰竭的临床疗效观察分析  

Clinical Effect Observation and Analysis of Qiangxin Composition on Treating Chronic Congestive Heart Failure

作　　者：孙兰军[1] 王保和[1] 赵英强[1] 张景江[2] 武重阳[3] 郑偕扣[1] 王瑞华[1] 

机构地区：[1]天津中医药大学第二附属医院,300150 [2]天津市北辰中医院,300020 [3]天津中医药大学,300193

出　　处：《天津中医药大学学报》2006年第3期146-148,共3页Journal of Tianjin University of Traditional Chinese Medicine

基　　金：国家中医药管理局科研基金课题(02-03LP17)。

摘　　要：[目的]通过临床试验、随访分析评价其治疗效果。[方法]采用随机、多中心、阳性药对照的原则,进行临床评价,随访研究分析强心冲剂的治疗效果。[结果]治疗组心功能、中医症状、Lee氏心力衰竭计分显效率分别为43.3%、43.3%、35.0%,总有效率为73.3%、83.3%、71.7%,对照组显效率分别为46.7%、35.0%、38.3%,总有效率为80.0%、81.7%、和80.0%。组间比较均P>0.05。选取部分病例随访,继续服药8周后其疗效优于服药4周。停药6个月后,治疗组、对照组、西药组的再住院率分别为3.2%、6.8%、6.67%,心血管大事件发生率分别为6.4%、6.8%、10.0%。[结论]强心冲剂的“益气温阳,活血利水”改善心衰症状,降低心衰患者的再住院率、心血管大事件的发生率,疗效确切。[Objective] To evaluation the curative effect of Qiangxin composition by using clinical experiment and follow-up analysis study. [Methods] To carry out clinical evaluation and follow-up analysis study on the curative effect of Qiangxin composition according to randomly, muhicentre and control of masccline medicine principle. [Results] The excellence rate of treatment group were individually 43.3%, 43.3%, 35% and total effective rate of treatment group were individually 73.3%, 83.3%, 71.7%, on the heart function, TCM symptoms and Lee scores of heart failure. The excellence rate of control group were individually 46.7%, 35%, 38.3% and total effective rate of treatment group were individually 80%, 81.7%, 80% on the heart function, TCM symptoms and Lee scores of heart failure. There weren＇t obviously differentiation between the treatment group and control group. To carry out follow-up study on the partly cases. The curative effect in eight weeks had an advantage than that in four weeks. The rehospitalization rate were individually 3.2%, 6.8%, 6.67% and the incidence rate of important heart vessel event were individually 6.4%, 6.8%, 10% in the treatment group, control group and western medicine group. [Conclusion] The Qiangxin composition have a definite curative effect on improving symptoms of heart failure, decreasing rehospitalization rate and the incidence rate of important heart vessel event in the heart failure patients.

关 键 词：慢性充血胜心力衰竭 强心冲剂 临床疗效 观察分析 

分 类 号：R692[医药卫生—泌尿科学]