静脉注射毒品人群中HIV、HBV和HCV感染的现况研究  

A study on the prevalence rates of human immunodeficiency virus, hepatitis B virus and hepatitis C virus infections in intravenous drug users

作　　者：王佑春[1] 许四宏[1] 李秀华[1] 宋爱京[1] 贾雪荣 庄辉[3] 

机构地区：[1]中国药品生物制品检定所,北京100050 [2]万泰生物医药公司 [3]北京大学医学部病原生物学系

出　　处：《中华流行病学杂志》2006年第9期777-779,共3页Chinese Journal of Epidemiology

基　　金：国家"十五"科技攻关课题资助项目(2004BA719A07)

摘　　要：目的了解静脉注射毒品人群中人类免疫缺陷病毒(HIV)、乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)的感染情况。方法从四川、湖南、广西和新疆等地静脉注射毒品人群中采集血液样本2025份,应用酶联免疫试剂盒检测抗-HIV、抗-HCV抗体和HBsAg。结果在静脉注射毒品人群中,抗-HIV、抗-HCV及HBsAg的阳性率分别为14．7％～30．4％、60．7％～85．5％和6．6％～22．4％,其HIV／HBV、HIV／HCV、HCV／HBV和HIV／HCV／HBV合并感染率分别为0％～0．4％、11．6％～27．2％、2．3％～14．3％和1．6％～4．8％。结论静脉注射毒品人群中HIV、HBV和HCV的感染率均高于正常人群,其中HIV与HCV合并感染率最高。Objective To study HIV, HBV and HCV infections in intravenous drug users. Methods 2025 blood samples from intravenous drug users were collected from Sichuan, Hunan, Guangxi and Xinjiang regions, and tested for anti-HIV, anti-HCV, HBsAg using enzyme linked immuno-sobent assays （ELISAs）. Results The positive rates of anti-HIV, anti-HCV and HBsAg were 14.7 %-30.4 % , 60.7 % -85.5 % and 6.6%-22.4% in the intravenous drug users, respectively. The co-infection rates of HIV/HBV, HIV/HCV, HCV/HBV and HIV/HCV/HBV were 0%-0.4%, 11.6%-27.2%, 2.3%- 14.3% and 1.6%-4.8% respectively in this population. Conclusion The infection rates of HIV, HBV and HCV were higher in the intravenous drug users than that in general populations in the same regions, and HIV/HCV co-infection appeared most frequent in this population.

关 键 词：人类免疫缺陷病毒 乙型肝炎病毒 丙型肝炎病毒 合并感染 

分 类 号：R181.3[医药卫生—流行病学]